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Impact of Regional Anesthesia on Blood Pressure in Humeral Fracture Surgery

Impact of Regional Anesthesia on Blood Pressure in Humeral Fracture Surgery : Comparative Study Using Propensity-score

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05153902
Acronym
ALR_HUMERUS
Enrollment
250
Registered
2021-12-10
Start date
2021-12-01
Completion date
2022-03-01
Last updated
2022-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proximal Humeral Fracture

Keywords

Surgery, General Anesthesia, Regional anesthesia, Hypotension

Brief summary

This study aims to compare the hemodynamic impact of two anaesthetic strategies : Regional anesthesia versus General anesthesia in proximal humeral fracture surgery.

Detailed description

Proximal humeral fracture surgery is frequently performed under General Anesthesia (GA). GA is frequently associated with a high risk of hypotension with significant consequences. Regional anesthesia could be an interesting alternative to GA in order to limit hemodynamic consequences, especially in elderly patients. Furthermore, in the current state of Covid 19 crisis, regional anesthesia could provide solutions in exposing less medical staff on patient's airway. The investigators hypothesize that the use of Regional anesthesia reduces the use of intraoperative vasopressor during surgery. After ethical committee approval, a retrospective cohort of patients with proximal humeral fracture, in Montpellier's University Hospital, was analyzed from 2016 to 2020. An informational note was given to all patients participating to the study.

Interventions

None listed

Sponsors

University Hospital, Montpellier
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* ASA I - IV * Proximal humeral fracture * Operated between january 2016 and december 2020 * Emergency surgery

Exclusion criteria

* Surgical revision or surgery for pre-existing infection, tumour * Intubated patient / unconscious patient * Haemostasis disorder * Haemostasis disorder * Refusal of the patient

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants requiring vasopressors in peroperativeduring surgery (between anaesthethic induction and end of surgical procedure)Number of Participants who used vasopressors in peroperative

Secondary

MeasureTime frameDescription
Total time spent on vasopressorduring surgery (between anaesthethic induction and end of surgical procedure)Total time spent on vasopressor
Intraoperative complicationsduring surgery (between anaesthethic induction and end of surgical procedure)Intraoperative complications other than hypotension
Postoperative complicationsbetween surgery and 2 days post-operativenausea/vomiting; cardiovascular complications; complications related to regional anesthesia ; postoperative cognitive disorders
Total dose of vasoconstrictorduring surgery (between anaesthethic induction and end of surgical procedure)Total dose of vasoconstrictor
Total time spent in the operating roombetween arrival in the operating room and discharge from the operating roomTotal time spent in the operating room
Length of stay in duty or ICUbetween the day of surgery and up to 1 monthLength of stay in duty or ICU
total dose of rescue analgesiabetween discharge from operating room and 24h post-operativeopioids

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026