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An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients

NLP Headache Open: an Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05153876
Acronym
NLPH-OPEN
Enrollment
1150
Registered
2021-12-10
Start date
2021-10-11
Completion date
2024-01-01
Last updated
2024-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cluster Headache, Headache Disorders, Migraine Disorders, Secondary Headache Disorder, TACS, Tension-Type Headache

Keywords

Migraine, Natural Language Processing, Headache

Brief summary

Headache disorders are among the most prevalent medical conditions worldwide. The diagnosis of headache disorders is based on medical history taking. Digital solutions such as natural language processing (NLP) may be of aid to understand the linguistic aspects of headache attack and headache related disability descriptions by patients. Participants will provide a written description of their headache disorder. The results will hopefully lead to a better understanding of the potential use of NLP in headache disorders.

Interventions

OTHERQuestionnaires

Headache attack descriptions, Headache related disability descriptions, Questionnaires, MIDAS, MSQv2.1, SF36

Sponsors

University Hospital, Ghent
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 year or older * Have a headache disorder with at least one headache attack over the last three months * voluntary participation * accepted the patient information sheet and gave informed consent

Design outcomes

Primary

MeasureTime frameDescription
Lexical diversity and differences between migraine and cluster headachethrough study completion, an average of 1 yearChi-square measurement of a word token used by migraine patients versus cluster headache patients

Secondary

MeasureTime frameDescription
F1 scores of machine learning experiments for the correct classification of headache disordersthrough study completion, an average of 1 yearMachine learning experiments to investigate the potential to build modelling algorithms that accurately classify the self-given diagnosis by the patient based on text.
Word countsthrough study completion, an average of 1 yearCounts of word tokens of different headache disorder groups
Sentences countsthrough study completion, an average of 1 yearCounts of sentence tokens of different headache disorder groups
Paragraph countsthrough study completion, an average of 1 yearCounts of paragraph tokens of different headache disorder groups
Accuracy of machine learning experiments for the correct classification of headache disordersthrough study completion, an average of 1 yearMachine learning experiments to investigate the potential to build modelling algorithms that accurately classify the self-given diagnosis by the patient based on text.
Migraine Disabillity Assessment [MIDAS] score calculation with text inputthrough study completion, an average of 1 yearMachine learning experiments to investigate the potential to build modelling algorithms that accurately predict the impact score from Migraine Disabillity Assessment \[MIDAS\] based on text.
Migraine Specific Questionaire versie 2.1 [MSQv2.1] score calculation with text inputthrough study completion, an average of 1 yearMachine learning experiments to investigate the potential to build modelling algorithms that accurately predict the impact score from Migraine Specific Questionaire versie 2.1 \[MSQv2.1\] based on text.
RAND SF-36 Dutch version score calculation with text inputthrough study completion, an average of 1 yearMachine learning experiments to investigate the potential to build modelling algorithms that accurately predict the impact score from RAND SF-36 Dutch version based on text.
Term-frequency inverse document frequency scores (TF-IDF)through study completion, an average of 1 yearTF-IDF scores of word tokens of different headache disorder groups

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026