Parkinson´s Disease, Aerobic Exercise and Photobiomodulation

Parkinson´s Disease, Aerobic Exercise and Photobiomodulation: a Randomised Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05152706

Acronym

PDAERPBM

Enrollment

Registered

2021-12-10

Start date

2021-01-10

Completion date

2024-06-30

Last updated

2024-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease

Brief summary

The aim of the present study was to assess the effects of a combined therapy of aerobic exercise and transcranial photobiomodulation upon the cardinal motor sympomts of Parkinson´s disease of a group of Parkinson´s disease patients. It was hypothesized that aerobic exercise and transcranial photobiomodulation would yield significant benefits in the cardinal motor sympomts of the illness.

Interventions

OTHERAerobic training

Cycling at the aerobic intensity

OTHERPhotobiomodulation

Photons therapy

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Diagnosis with idiopathic PD and rated 1-2 on the Hoehn and Yahr Scale. * No type of dementia as assessed by the mini-mental state examination. * Able to stand for 2 min without assistance. * Able to walk 10 m without assistance.

Exclusion criteria

* Individuals were excluded if they suffered a neurological disease other than PD, if the subject has an implant of any kind in the head (e.g., stent, clipped aneurysm, embolized arteriovenous malformation, implantable shunt - Hakim valve) or if they did not meet the eligibility criteria.

Design outcomes

Primary

Measure	Time frame	Description
MDS-UPDRS	6 months	The motor portion of the Movement Disorder Society-Unified Parkinson´s (MDS-UPDRS, the minimum and maximum values are 0 and 72, respectively and the higher score, the worse patient condition)

Secondary

Measure	Time frame	Description
DASH	6 months	The disabilities of the arm, shoulder and hand (DASH, the minimun and maximum values are 0 and 190, respectively and the higher score, the worse patient condition)
Static posturography	6 months	The centre of pressure (CoP) parameters (these CoP parameters; Length, in mm, Area in mm2 and Speed, Xspeed and Yspeed in m/s will be combined to report the static posturography)
TMWT	6 months	10 meters walking test (speed in seconds)
TUG	6 months	Time up Go Test (speed in seconds)
Grip strength	6 months	Grip strength in kg

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026