Continuation of Aspirin Before Isolated Heart Valve Surgery

Effect of Continuation of Aspirin Before Isolated Heart Valve Surgery on Postoperative Bleeding and Transfusion: a Single-center Retrospective Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05151796

Enrollment

500

Registered

2021-12-09

Start date

2012-05-01

Completion date

2021-12-01

Last updated

2021-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Isolated Heart Valve Surgery

Brief summary

Whether or not continuing aspirin up to de day before surgery increases the risk of bleeding and/or prevents thrombo-embolic complications remains debated. The investigators retrospectively investigated the whether continuing aspirine within 5 days of isolated heart valve surgery increased the risk of bleeding.

Interventions

DRUGAspirin

Daily aspirin intake for cardiovascular prevention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Isolated heart valve surgery

Exclusion criteria

* Antiplatelet agent other than aspirin or anticoagulant not discontinued preoperatively * Emergent or salvage surgery * Surgery for endocarditis * Use of NSAIDs within 48 hours before surgery

Design outcomes

Primary

Measure	Time frame
The number of units of packed red blood cells transfused anytime during the hospital stay	30 days

Secondary

Measure	Time frame	Description
Chest tube drainage	24 hours	volume of chest tube drainage
Surgical revision for bleeding	24 hours	—
Any thrombo-embolic complication	30 days	—
Transfusion of any type of blood product	30 days	—

Countries

Belgium

Contacts

Primary ContactGregory Hans, MD

G.Hans@chuliege.be

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026