Acute Kidney Injury, Chronic Kidney Diseases, Dialysis; Complications
Conditions
Brief summary
Retrospective observational study to investigate acute kidney injury (AKI) epidemiology and outcomes in patients hospitalized in University Hospital San Martino, Genova, Italy.
Detailed description
A retrospective observational study was designed to investigate acute kidney injury (AKI) epidemiology and outcome in patients hospitalized in University Hospital San Martino, Genova, Italy. All data will be extracted from the hospital electronic database. The investigators will evaluate demographic, clinical and laboratory data, including age, sex, serum creatinine (sCr), sodium and electrolytes, intensive care unit (ICU) admission, length of hospital stay, death, comorbidities and primary diagnosis codes at the hospital discharge (using International Classification of Diseases-ICD-9- codes). The investigators will include also patients affected by Coronavirus disease 19 (COVID-19). The primary endpoint will be to describe AKI epidemiology, secondary endpoints will be to evaluate AKI-related risk factors and clinical outcomes, such as length of stay and mortality. Moreover, the investigators will describe the differences in the outcome and treatments of AKI patients in the medical wards and ICU.
Interventions
OTHERData collection
Collection and analysis of data related to AKI epidemiology, treatment and outcomes
Sponsors
Ospedale Policlinico San Martino
Universita degli Studi di Genova
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients admitted to University Hospital San Martino, Italy * We'll include also patients affected by Coronavirus disease 19 (COVID-19).
Exclusion criteria
* Hemodialysis patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Acute Kidney Injury incidence | Collection of retrospective data from 2016 | Rate of in-hospital Acute Kidney Injury incidence |
| Acute Kidney Injury severity | Collection of retrospective data from 2016 | Staging of in-hospital Acute Kidney Injury according to the KDIGO guidelines |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality in Acute Kidney Injury patients | Collection of retrospective data from 2016 | Rate of in-hospital mortality among patients with Acute Kidney Injury |
| Creatinine clearance after discharge | Collection of retrospective data from 2016 | Data on kidney function after the discharge in Acute Kidney Injury patients |
Countries
Italy
Contacts
Primary ContactPasquale Esposito
Outcome results
None listed