Multicenter Cohort Study of Invasive Fungal Filamentous Fungal Infections in Liver Transplant Patients

Multicenter Retrospective Cohort Study of Invasive Fungal Filamentous Fungal Infections in Liver Transplant Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05150327

Acronym

FongiFoie

Enrollment

300

Registered

2021-12-09

Start date

2021-10-29

Completion date

2024-09-01

Last updated

2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fungal Infection

Keywords

Fungal Infection, Immunodeficiency, Fungal filamentous, Liver transplant, Organ transplant

Brief summary

Invasive filamentous fungal infections (aspergillosis, scedosporiosis, mucormycosis, fusarium wilt) are frequent and serious in immunocompromised individuals and especially in organ transplant patients. There is little recent data in liver transplantation, especially on the incidence and risk factors of fungal infections

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age: from birth * Subject with a liver transplant in one of the centers participating in the study * Invasive fungal infection with filamentous fungus between 2007-2021 * Proven or probable infection with filamentous fungi according to EORTC/MSGERC criteria: * Invasive aspergillosis * Mucormycosis * Fusariosis * Scedosporiosis * Other infection with filamentous fungus * Subject or legal representative for minors, who has not expressed, after information, his opposition to the reuse of his data for scientific research purposes.

Exclusion criteria

* Subject or (legal representative for minors) who has expressed his opposition to participating in the study * Subject not with a liver transplant * Subject under guardianship, curatorship or legal protection

Design outcomes

Primary

Measure	Time frame
Study of the incidence, risk factors and prognostic factors associated with invasive fungal filamentous fungal infections in liver transplant patients.	Files analysed retrospectively from January 01, 2007 to December 31, 2021 will be examined]

Countries

France

Outcome results