COVID-19, Olfactory Dysfunction
Conditions
Keywords
COVID-19, olfactory dysfunction, Gustatory dysfunction, Corticosteriods
Brief summary
Coronavirus is a global pandemic with a high mortality rate; it is started in china in 2019 and rapidly spread worldwide, reaching its epidemic peak in March 2020 Coronavirus is a family of viruses that usually affect animals. They also can affect the respiratory system of humans, causing different manifestations such as difficulty in breathing, coughing, fever, invasive lung lesions, and viral pneumonia
Detailed description
Coronavirus is a global pandemic with a high mortality rate; it is started in china in 2019 and rapidly spread worldwide, reaching its epidemic peak in March 2020 Coronavirus is a family of viruses that usually affect animals. They also can affect the respiratory system of humans, causing different manifestations such as difficulty in breathing, coughing, fever, invasive lung lesions, and viral pneumonia Smell and taste dysfunction is more frequent in the initial stages of covid-19 infection that occur within the first five days and may be used as pivotal symptoms in the early diagnosis of the disease
Interventions
DRUGAdministration of Systemic Corticosteroid
10 mg of systemic corticosteroids were prescribed weekly to patients to observe taste and smell sensation recovery.
Sponsors
Fayoum University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
67 Covid-19 patients with symptoms of ageusia and anosmia were recruited (that their covid infection was confirmed by using PCR).
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* all signs and symptoms were recorded included fever \>38 °C, fatigue, myalgia, arthralgia, sore throat, headache, and its localization (diffuse, frontal, other localization), rhinorrhea, nasal obstruction, epistaxis, tinnitus, and hearing loss, sneezing, cough, sputum production, hemoptysis, dyspnea, respiratory rate \>22, crackling sounds during auscultation, nausea, vomiting, diarrhea, and abdominal pain.
Exclusion criteria
* patients with absolute contraindications for systemic corticosteroids administration, pregnant women, smokers, and patients with any systemic disease or taking any medications that cause loss of taste or smell were excluded from this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Taste sensation | 3 months | recovery of taste sensation by questionnaire |
Countries
Egypt
Outcome results
None listed