Prenatal Screening of Intestinal Malrotation With a Higher Risk of Volvulus.

Prenatal Screening of Intestinal Malrotation With a Higher Risk of Volvulus: Value of the Ultrasound Study of the Relative Position of the Superior Mesenteric Vessels and Fetal Abdominal MRI.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05148429

Acronym

MALROT

Enrollment

Registered

2021-12-08

Start date

2020-01-01

Completion date

2021-11-01

Last updated

2021-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postnatal Complication, Mesenteric Pregnancy

Keywords

Pregnant women, 2nd trimester ultrasound examination, Mesenteric vessels positionning, Pediatric follow up +/- treatment, Postnatal confirmation, Evolution and complication

Brief summary

Digestive malrotation is an anatomical anomaly of the positionning of the mesenteric vessels and the digestive tract that can lead in some form to a dangerous neonatal complication: intestinal volvulus. This requires emergency surgery with a risk of digestive resection. Visualizing during pregnancy the normal or abnormal anatomical positionning of the mesenteric vessels could make it possible to diagnose this malrotation and prevent the occurrence of this complication. The aim of the study is to study the neonatal outcome of fetus confirm to have an abnormal positionning of mesenteric vessels

Interventions

OTHERUltrasound exam

Ultrasound exam

OTHERFetal MRI

Fetal MRI

OTHERPostnatal abdominal ultrasound

Postnatal abdominal ultrasound

OTHERPediatric Follow up

Pediatric Follow up

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Pregnant women attending for 2nd trimester ultrasound * Abnormal positionning of mesenteric vessels * No other foetal malformation * Singleton pregnancy * Age \>18 years

Exclusion criteria

* Chromosomal abnormality * polymalformative syndrom * Foetal malformation changing intestine disposition (gastroschisis, diaphragmatic hernia, heterotaxis…)

Design outcomes

Primary

Measure	Time frame	Description
Percentage of intestinal malrotation among foetuses	day 1	Percentage of intestinal malrotation among foetuses with abnormal positionning of mesenteric vessels

Secondary

Measure	Time frame	Description
Rate of correlation between prenatal	day 1	Rate of correlation between prenatal
Rate of postnatal ultrasound	day 1	Rate of postnatal ultrasound
type of intestinal malrotation	day 1	type of intestinal malrotation

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026