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Selective Nerve Root Block With Ultrasound Guidance Improves Surgical Outcome of Selective Discectomy in Patients With Multilevel Cervical Disc Disease

Selective Nerve Root Block With Ultrasound Guidance Improves Surgical Outcome of Selective Discectomy in Patients With Multilevel Cervical Disc Disease: a Randomized Controlled Trial

Status
Completed
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05145530
Enrollment
60
Registered
2021-12-06
Start date
2017-08-10
Completion date
2020-04-30
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Selective Discectomy, Selective Nerve Root Block

Brief summary

Disc degeneration is a natural part of growing older. Up to 60% of asymptomatic people have MRI findings that are positive. As a result, MRI only provides morphological information and may not be able to determine the clinical significance of the findings.

Detailed description

Many authors believe that patients who suffer from cervical radiculopathy as a result of degenerative disease and have multilevel pathology on imaging studies still have moderate surgical outcomes. This occurs due to a misdiagnosis or the need to perform surgery on multiple levels despite a single painful lesion. Although the complication rate for 1- and 2-level ACDF is so low that it is considered one of the safest procedures in spine surgery. There is concern that increasing levels of fusion will lead to more complications, such as a higher incidence of persistent axial neck pain, dysphagia, and vertebral artery injury, as well as more postoperative pain and higher narcotic dosages.

Interventions

PROCEDUREselective anterior cervical discectomy and fusion (ACDF)

selective anterior cervical discectomy and fusion (ACDF)

PROCEDURESNRB+ selective anterior cervical discectomy and fusion (ACDF)

US-guided selective nerve root block (SNRB) + selective anterior cervical discectomy and fusion (ACDF)

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* all patients presented with unilateral brachialgia due to multilevel cervical disc disease

Exclusion criteria

* multilevel cervical disc disease who had bilateral brachialgia, * myelopathy, double crush syndrome, * ossified posterior longitudinal ligament (OPLL), * combined anterior and posterior pathology requiring posterior decompression

Design outcomes

Primary

MeasureTime frameDescription
pain intensity24 hours postoperativeVisual analogue score (VAS): 0= no pain, 10= worst pain

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026