Cardiopulmonary, Exercise
Conditions
Brief summary
To determine the validity of the K5 metabolic system breath-by-breath analysis setting during a high intensity treadmill running protocol compared to the criterion ParvoMedics TrueOne® 2400 automated metabolic gas analysis system. To determine the test-retest reliability of the K5 metabolic system breath-by-breath analyzer during a high intensity treadmill protocol (Bruce Protocol).
Interventions
DEVICECOSMED K5 CPET (Cardiopulmonary Exercise Test)
In this randomized crossover trial of eligible adults, we will compare peak measurements of oxygen consumption (VO2) and carbon dioxide production (VCO2) during three maximal cardiopulmonary stress exercise tests (CPET), each seven to ten days apart. Subjects will be randomized into either the K5 or ParvoMedics (PM) group for their first CPET using a 1:1 randomization scheme and will serve as their own control in the subsequent test seven to ten days after the previous one. After both a K5 and a PM CPETs have been completed, the participants will complete an additional K5 CPET for test-retest reliability. A within-subjects analysis will be performed.
DEVICEParvoMedics CPET
ParvoMedics CPET
Sponsors
Baylor Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 29 Years
Healthy volunteers
Yes
Inclusion criteria
* 20-29 years of age
Exclusion criteria
* Pregnancy * Children * Inmates * Neuromotor, musculoskeletal, or rheumatoid disorders that are exacerbated by exercise or conditions preventing cooperation * Contraindications to Symptom-limited Maximal Exercise Testing * Metabolic disease * Pacemakers/Implantable devices * Supplemental Oxygen use * Diagnosis of severe arterial hypertension * Uncontrolled asthma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen consumption (VO2), mL/min | At first assessment, during week one. | Using metabolic cart, VO2 will be recorded. |
| Carbon dioxide production (VCO2), mL/min | At first assessment, during week one. | Using metabolic cart, VCO2 will be recorded. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Breathing Reserve, % | At first assessment, during week one. | Using metabolic cart, breathing reserve will be recorded. |
| Tidal Volume, L | At first assessment, during week one. | Using metabolic cart, tidal volume will be recorded. |
| Respiratory Exchange Ratio (RER) | At first assessment, during week one. | Using metabolic cart, respiratory exchange ratio will be recorded. |
| Fractional expired oxygen (FEO2) | At first assessment, during week one. | Using metabolic cart, fractional expired oxygen will be recorded. |
| Fractional expired carbon dioxide (FECO2) | At first assessment, during week one. | Using metabolic cart, fractional expired carbon dioxide will be recorded. |
| Respiratory Frequency, /min | At first assessment, during week one. | Using metabolic cart, respiratory frequency will be recorded. |
| Minute Ventilation, L/min | At first assessment, during week one. | Using metabolic cart, minute ventilation will be recorded. |
Countries
United States
Outcome results
None listed