Skin Diseases
Conditions
Brief summary
The purpose of this study is to explore the evaluation of the efficacy of TCI66207 deep-sea live-face bacteria on the skin.
Interventions
DIETARY_SUPPLEMENTTCI66207 Essence
Use it twice a day after washing your face in the morning and evening for a total of 4 weeks.
DIETARY_SUPPLEMENTPlacebo Essence
Use it twice a day after washing your face in the morning and evening for a total of 4 weeks.
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. Healthy volunteers aged above 20 years old 2. Subject has dull skin.
Exclusion criteria
1. .Subject with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history). 2. Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder. 3. Female who is pregnant or nursing or planning to become pregnant during the course of the study. 4. Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks. 5. Subjects who have large spots (area \>3 square centimeter) or abnormal acne.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of skin moisture | Subjects will be tested in the 4th week. | Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120 |
| The change of skin elasticity | Subjects will be tested in the 4th week. | Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curvesCorneometer® units 0-120 |
| The change of skin wrinkles | Subjects will be tested in the 4th week. | VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units |
| The change of skin collagen density | Subjects will be tested in the 4th week. | DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units: Intensity score |
| The change of skin texture | Subjects will be tested in the 4th week. | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units |
| The change of skin pores | Subjects will be tested in the 4th week. | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units |
Countries
Taiwan
Outcome results
None listed