German Cardiac Arrest Registry

Conditions

Out-of-hospital Cardiac Arrest

Keywords

Out-of-hospital Cardiac Arrest, OHCA, resuscitation, cardiac arrest center, acute care medicine, intensive care, post-resuscitation care

Brief summary

In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes. Despite the medical progress over the last decades, rates of survival with good neurological outcome remain low. For many below-mentioned issues, no adequate evidence from randomized trials is available. Therefore, a systematic and standardized recording of the pre-clinical, clinical and post-clinical treatment course and of the clinical outcomes of OHCA patients is essential to improve patient care. Aim of the German Cardiac Arrest Registry (G-CAR) is to achieve a better understanding of the disease entity, leading to an optimized treatment of OHCA patients. The recorded data include information on demographic and psychosocial aspects, course of the disease, clinical, laboratory and other examinations as well as treatment modalities in patients with OHCA due to a cardiac cause.

Roßberg M, Heerklotz H, Hösler N, Ouarrak T, Desch S, Thiele H, Zeymer U, Tigges E, Voigt I, Michels G, Voss F, Apfelbacher C, Freund A, Ewen S, Fleischmann-Struzek C, Sinning C, Pöss J, G-CAR Investigators.

2026-08-24

10.1016/j.resuscitation.2026.111277

German Cardiac Arrest Registry (G-CAR)-results of the pilot phase.

Pöss J, Sinning C, Roßberg M, Hösler N, Ouarrak T, Böttiger BW, Ewen S, Wienbergen H, Voss F, Dutzmann J, Tigges E, Voigt I, Freund A, Desch S, Michels G, Thiele H, Zeymer U, G-CAR Investigators.

2024-06-131 citations

10.1007/s00392-024-02468-5

German Cardiac Arrest Registry: rationale and design of G-CAR

Janine Pöss, Christoph Sinning, Isabelle Schreiner, Christian Apfelbacher, Karl Philipp Drewitz et al. (22 authors)

Clinical Research in Cardiology2022-06-218 citations

10.1007/s00392-022-02044-9

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* patients with out-of-hospital cardiac arrest with assumed cardiovascular cause

Exclusion criteria

* rejection of register participation by patient or legal representative

Design outcomes

Primary

Measure	Time frame
In hospital mortality	until discharge, an average of 2 weeks

Secondary

Measure	Time frame	Description
Length of ICU stay	until discharge, an average of 2 weeks	—
Length of hospital stay	until discharge, an average of 2 weeks	—
Mortality	Day 30	—
European Quality of Life 5 Dimensions 5 Level Version (EQ-5D)	Month 6	five levels in each dimension are worded as (1) 'not /no problems', (2) 'slight problems', (3) 'moderate problems', (4) 'severe problems', and (5) 'unable to'
Post Traumatic Stress Syndrome	Month 6	PTSS-14
Reintegration	Month 6	Reintegration to Normal Living Index
Hospital Anxiety and Depression Scale (HADS)	Month 6	score 0-21; higher value show more severe depression
Mini Montreal Cognitive Assessment (MoCA)	Month 6	score 0-15; 11 or higher is normal, 10 or less indicate cognitive dysfunction
Post Traumatic Stress Syndrome (PTSS-14)	Month 12	scor 14-98; higher value indicate more post traumatic stress

Countries

Germany

Contacts

CONTACTJanine Pöss, Dr.

janine.poess@medizin.uni-leipzig.de+49 341 865

CONTACTHolger Thiele, Prof.

holger.thiele@medizin.uni-leipzig.de+49 341 865

STUDY_CHAIRJanine Pöss, Dr.

Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology

Outcome results