Elbow Stiffness, Tranexamic Acid
Conditions
Brief summary
This study is a prospective randomized controlled study of different arthroscopic treatments for elbow stiffness combined with tranexamic acid(TXA) injection. The patients with stiffness were randomly divided into groups before the operation. After the arthroscopic operation was completed, they were divided into a local TXA injection group and a control group (normal saline) to perform additional operations for reduction of hemorrhage. In different time periods, the quantitative and qualitative indicators including pain, functional score, range of motion, level of Hemoglobin, the circumference of the limb 10cm above and below the elbow, amount of hemorrhage, etc. were compared between groups at the same time period to evaluate the difference in the effect of arthroscopic treatment combined with TXA on the treatment of reduction of hemorrhage. Determine the effectiveness of TXA.
Interventions
DRUGTXA
After the arthroscopic operation was completed, a local TXA injection was performed
DRUGSaline
After the arthroscopic operation was completed, a local saline injection was performed
Sponsors
Beijing Jishuitan Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Clinically diagnosed patients with elbow stiffness Young and middle-aged patients aged 18 to 60 with failed nonoperated treatment Voluntarily accept randomized controlled grouping, cooperate with treatment and follow up patients No other comorbidities or medical diseases affect the surgical patients -
Exclusion criteria
Elderly people older than 60 years old and patients younger than 18 years old With severe comorbidities or medical diseases affect the surgical patients \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mayo Elbow Performance Score | baseline-6 months postoperatively | A score used to evaluated the elbow function |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale | baseline-6 months postoperatively | A score used to evaluated the pain |
| Circumference of upper extremity | baseline-6 months postoperatively | — |
| change of hemoglobin | baseline-6 months postoperatively | — |
| range of motion | baseline-6 months postoperatively | flexion, extension, pronation and supination of elbow |
Countries
China
Contacts
Primary ContactShangzhe Li, M.D.
Outcome results
None listed