Anesthesiology, Corticosteroids, Respiratory Complication, Thoracic Surgery
Conditions
Keywords
Thoracic surgery, Anesthesiology, Corticosteroids, Respiratory Complication
Brief summary
Thoracic surgery is at high risk of respiratory complications. Despite the improvement of surgical procedures such as video-thoracoscopy, respiratory complications appear in 15 to -20% of procedures. Thoracic surgery induces local pulmonary inflammation which is involved in the occurrence of post-operative respiratory failure. Similarly to the example of the acute respiratory distress syndrome, corticosteroids could reduce lung injury secondary to immunological stress. In addition, recent studies suggest that dexamethasone could lead to a reduction of respiratory complications after major non cardiothoracic surgery. Since dexamethasone is recommended to prevent postoperative nausea and vomiting, around one in two patients receive dexamethasone during anesthetic induction. By retrospective analysis with compensation of bias by propensity score, the investigators aim to assess the effect of dexamethasone to prevent respiratory complications
Interventions
None listed
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age : minimum 18 years old * Patients who underwent scheduled lung resection surgery
Exclusion criteria
* absence of patient's consent * age under 18 years * pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of respiratory failure rates between patients receiving or not DEXAMETHASONE | 7 days following surgery |
Countries
France
Outcome results
None listed