Craniofacial Pain, Post Operative Pain
Conditions
Keywords
sphenopalatine ganglion block, post-craniotomy pain
Brief summary
Post craniotomy pain is defined as headache developed up to 7 days from a craniotomy, not otherwise explained. A moderate to severe pain affects from 60 to 84% of patients. Sphenopalatine ganglion block has been successfully used in patients with chronic or acute headache, facial pain and for transsphenoidal pituitary and endoscopic sinus surgeries. There are evidences that sphenopalatine ganglion block reduces vegetative responses to skull pin closure. This study aim to investigate feasibility and efficacy of sphenopalatine ganglion block in reducing pain after a neurosurgical supratentorial craniotomy.
Interventions
DRUGSphenopalatine ganglion block
A cotton swab soaked in levobupivacaine 7,5% in inserted into the nose to block sphenopalatine ganglion, with the classic technique previously described
Troncular scalp blockade. Local site infiltration
Sponsors
University Hospital of Ferrara
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* supratentorial craniotomy
Exclusion criteria
* prior craniofacial pain syndrome * drug assumption: pain-killers (chronic), antiepileptic
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Numerical Rating Scale | Immediately post-op | From 0 (no pain) to 10 (worst pain ever) |
| Visual Analogic Scale | Immediately post-op | From 0 (no pain) to 10 (worst pain ever) |
| Pain Assessment IN Advanced Dementia | Immediately post-op | From 0 (no signs of pain) to 10 (Extreme pain) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse effect | Immediately post-op, 1°-2°-3°-4°-30°-60°180° days post-op | Bitter taste, nose bleeding, throat discomfort |
| Vegetative response (Heart rate) | 1-5-10 min from skull pin closure. 1-5-10 min from skin incision | Heart rate in beat per minute |
| Vegetative response (Arterial pressure) | 1-5-10 min from skull pin closure. 1-5-10 min from skin incision | Mean arterial pressure in mmHg |
Countries
Italy
Contacts
Primary ContactAlba Scerrati, MD
Backup ContactGiorgio Mantovani, MD
Outcome results
None listed