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Lucerne Fall Risk Prediction Score for Stroke Rehabilitation

Lucerne Fall Risk Prediction Score for Stroke Rehabilitation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05135884
Acronym
L-PRESTO
Enrollment
328
Registered
2021-11-26
Start date
2019-09-01
Completion date
2021-09-30
Last updated
2021-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Brief summary

In Switzerland, every year around 16'000 people suffer a stroke. Stroke represents the third most common cause of death in Switzerland and leads to impairments (e.g., motoric, cognitive, sensory) resulting in disability. People with disabilities after stroke should have access to specialised interprofessional rehabilitation settings. During inpatient rehabilitation, 15-36% of the patients experience one or more falls. It is well known that stroke is an important risk factor for falls. On average stroke patients fall 1.77 times more than the age- and gender-matched controls over 13 months. Falling events during inpatient stroke rehabilitation result in an extension of rehabilitation stay of about eleven days. Wong et al. (2016) suspect that a reduction in the activity level due to falls, fear of falling again as well as changes in discharge conditions could be the reason for this extended length of stay. Walsh et al. (2018) demonstrate that patients who fall once within the first year after stroke cause € 8'600 and recurrent fallers € 12'700 higher healthcare costs. Fall risk factors after stroke are well investigated. Campbell & Matthews (2010) have collected multiple factors for falls in inpatient stroke rehabilitation from 1990 to 2009 in an integrative review. A newer systematic review points out physical function, hemi-attention, and stability as the most important factors for falls in inpatient stroke rehabilitation. However, none of the included studies showed a validated prediction model with acceptable performance. Hence, further investigations regarding the impact of various valid and reliable fall risk assessments at admission in inpatient rehabilitation are needed. The neurorehabilitation team of LUKS systematically assesses the patient's functions and activity to design patient-specific, evidence-based rehabilitation. Therefore, a population-specific fall risk model based on standardized assessments performed in the clinical routine would help to identify patients with a high risk of falling during rehabilitation without the need of implementing an existing model with a low performance. Aim of the study The main aim of this study is to establish a multivariable prediction model for falls during inpatient rehabilitation in acute and subacute stroke patients admitted to the Clinic for Neurology and Neurorehabilitation of the Kantonsspital Luzern (LUKS) in Lucerne, Switzerland. The secondary aim is to explore the value of the mini-BESTest as a fall predictor in a subgroup consisting of patients who are ambulatory at admission to the Clinic for Neurology and Neurorehabilitation.

Interventions

BEHAVIORALStandard inpatient stroke rehabilitation

According to Swiss national guidelines and local protocols

Sponsors

Luzerner Kantonsspital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Acute/ subcute first or recurrent stroke * Inpatient rehabilitation * Signed general consent

Exclusion criteria

\- Re-rehabilitation due to a chronic stroke

Design outcomes

Primary

MeasureTime frameDescription
Occurance of at least one fallDuring inpatient stroke rehabilitation, an average of 6 weeksEvent of least one fall (yes/ no) during inpatient stroke rehabilitation

Secondary

MeasureTime frameDescription
2-Minute Walk Test (meter, higher scores being better)Rehabilitation admissionGait speed and walking distance
Timed up and go (seconds, lower scores being better)Rehabilitation admissionMobility
Lucerne ICF Based Multidisciplinary Observational Scale (45-225 points, higher scores being better)Rehabilitation admissionActivities of daily living
Functional Independence Measure (18-126 points, higher scores being better)Rehabilitation admissionActivities of daily living
Mini Balance Evaluation Systems Test (0-28 points, higher scores being better)Rehabilitation admissionBalance
Apraxia Screen of Tulia (0-12 points, higher scores being better)Rehabilitation admissionApraxia
Catherine Bergego Scale (0-30 points, lower scores being better)Rehabilitation admissionVisuospatial function
Language Screening Test (0-15 points, higher scores being better)Rehabilitation admissionSpeech function
Montreal Cognitive Assessment (0-30 points, higher scores being better)Rehabilitation admissionCognitive function

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026