IMAGE, PET/CT, Prostate Specific Membrane Antigen
Conditions
Brief summary
Dual-time point 68Ga-PSMA PET/CT could increase the lesion detection in PCa patients, it remains difficult to perform in clinical practice. The possibility of one-time point 68Ga-PSMA PET/CT imaging could be achieved using a total-body PET/CT.
Interventions
DEVICEtotal-body PET/CT
PCa patients who underwent PSMA PET/CT in our clinical center received two-time points scans at 1 h p.i. and 3 h p.i. on a total-body PET/CT scanner.
Sponsors
RenJi Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Healthy volunteers
No
Inclusion criteria
* primary staging of pathology-confirmed PCa or evidence of BCR with PSA value \> 0.2 ng/ml * positive 68Ga-PSMA findings * both standard and delayed scans were performed on the total-body PET/CT
Exclusion criteria
* only one scan was performed * negative PSMA results
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Only one-time point scan is possible for PSMA PET/CT | 8 months | By the use of total- body PET/CT scanner, the imaging quality between the 1 h p.i. and 3 h p.i. imaging acquisition are compared. And the different lesion detection rates at 3 h p.i. and 1 h p.i. are also discussed. The uptake value differences of all lesions are compared. |
Countries
China
Outcome results
None listed