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Lung Ultrasound Assessment of Fluid Overload in Haemodialysis Patients

Lung Ultrasound Assessment of Fluid Overload in Haemodialysis Patients Using 8 Sites Score

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05132036
Acronym
EP8SH
Enrollment
46
Registered
2021-11-23
Start date
2021-11-09
Completion date
2022-06-01
Last updated
2025-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis Complication, Lung Ultrasound

Keywords

Lung ultrasound, Hemodialysis Complication, hemodialysis ultrafiltration volume

Brief summary

Determination of the hemodialysis ultrafiltration volume is guided by the clinician's estimate of dry weight. A poor estimate of this dry weight may result in insufficient fluid depletion causing a state of volume overload, which may be associated with long-term left ventricular failure, high blood pressure and excess of mortality. The diagnosis of fluid overload in haemodialysis patient is routinely based on clinical examination which consists of cardiopulmonary auscultation and edema palpation of limb member. Clinical examination can be completed by paraclinical examinations, and bioimpedance is an objective tool that assess fluid overload state. This test provides an individualized hydration status and fluid overload based on normal extracellular volume considering body composition. Echocardiography allows an accurate assessment of blood volume status by simultaneous studying left ventricular filling pressures, systolic pulmonary artery pressure and the diameter of the inferior vena cava. Lung ultrasound analyses the B-lines defined as artefactual images resulting from contact between air in alveoli and water in septa. It can estimate pulmonary congestion. The aim of the study is to evaluate the lung ultrasound using 8 sites score accuracy for estimating fluid overload of patients before hemodialysis session.

Interventions

OTHERlung ultrasound

Subjects are enrolled during their usual session in the hemodialysis unit of the Amiens University Hospital. Before starting the hemodialysis, lung ultrasound according to the 8 sites score and a measure of bioimpedance will be performed in dorsal decubitus. In a 2nd time, an echocardiography is realized. During haemodialysis session, biological analysis and clinical score will be assessed

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age over 18 years old * patients on hemodialysis for more than 3 months; * patients without cardiological or infectious event for at least 3 months; * patients having at least 2 dialysis session per week; * patients affiliated with a health insurance plan; * patients having signed an informed consent.

Exclusion criteria

* Pulmonary fibrosis or active lung disease; * residual diuresis over 500 mL per day; * body mass index (BMI) \< 21 and \> 28 Kg/m²; * medical history of major amputation (subgonal or transfemoral); * pacemaker carrier; * patients with orthopedic prosthesis.

Design outcomes

Primary

MeasureTime frameDescription
number of patients with fluid overloadone dayFluid overloaded are determined by both tecniques : estimated fluid overload and lung ultrasound measured fluid overload

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026