Incidence , Risk Factors and Outcomes of Haemodynamic Instability and Cardiac Arrest During Spine Surgery

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05131854

Enrollment

100

Registered

2021-11-23

Start date

2021-11-25

Completion date

2022-12-31

Last updated

2022-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spine Surgery

Keywords

spine surgery , bradycardia , cardiac arrest

Brief summary

Risk factors for cardiac arrest during spine surgery have been well defined, including lumbar fusion, age over 65 years, obesity, cardiovascular disease, ethnicity and ASA status. Bradycardia and asystole have been described under general anaesthesia in combined surgical cohorts: Proposed mechanisms include unopposed parasympathetic activation, enhanced vasovagal response to decreased venous return, and psychiatric stressors. The investigators prospectively will review patients candidates for spine surgery to explore potential incidence, contributory factors and outcomes to unexpected transient intraoperative haemodynamic instability, arrhythmia, and cardiac arrest during spine surgery as these data are needed to aid risk stratification and improve decision making for spine care teams.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

1. Aged more than 18 2. Gender: both. 3. ASA grade I-II (American society of anesthiologists). 4. Prepared to spine surgery under general anesthesia

Exclusion criteria

1. Ischemic heart patients 2. Hypertensive patients 3. Patients with atrial fibrillation or any previous history of attack of arrhythmias 4. Patients on B.B ( beta-blockers) 5. Chronic use of neuropsychiatric medications 6. Renal Impairment 7. Liver Dysfunction. 8. Any complications during the procedure as massive hemorrhage 9. Surgery for traumatic spinal cord

Design outcomes

Primary

Measure	Time frame	Description
Incidence of Haemodynamic Instability during Spine Surgery	allover one year	To calculate Incidence of Haemodynamic Instability during Spine Surgery
Risk factors of Haemodynamic Instability during Spine Surgery	allover one year	To analyze risk factors of Haemodynamic Instability during Spine Surgery
outcomes of Haemodynamic Instability during Spine Surgery	allover one year	To calculate the rate of mortality of Haemodynamic Instability during Spine Surgery
Incidence of cardiac arrest during Spine Surgery	allover one year	To calculate Incidence of cardiac arrest during Spine Surgery
Risk factors of cardiac arrest during Spine Surgery	allover one year	To analyze risk factors of cardiac arrest during Spine Surgery
outcomes of Cardiac Arrest during Spine Surgery	allover one year	To calculate the rate of mortality of cardiac arrest during Spine Surgery

Countries

Egypt

Contacts

Primary ContactEssamedin Negm, MD

alpherdawss@gmail.com0021098123058

Backup ContactEssam youssef

0021002815325

Outcome results