Impaired Attention
Conditions
Brief summary
Banana peel has the potential to improve sleep quality. The purpose of this research is to test the effect of banana peel on improving sleep quality.
Detailed description
Insomnia is one of the most frequently complained sleep problems in sleep disorders, and in recent years has been regarded by the medical community as a disease that seriously affects people's lives and quality of life. The problem of perishable and perishable causes a great burden on the environment. However, banana peels actually contain many functional ingredients, such as dietary fiber, minerals, alkaloids, flavonoids, phenols, saponins, tannins and dopamine, etc. Banana peel contains more total phenols and total flavonoids than banana pulp. Studies have pointed out that banana peel extraction can inhibit the growth of fungi and bacteria. In addition, it also has antioxidant, anti-depressant, and diuretic functions. Banana peel can also improve the performance of tryptophan metabolism-related genes
Interventions
DIETARY_SUPPLEMENTPlacebo
take 2 tablets 2 hours before bedtime for 4 consecutive weeks
DIETARY_SUPPLEMENTBanana peel extract
take 2 tablets 2 hours before bedtime for 4 consecutive weeks
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1.20 to 65-year-old males or non-pregnant females who are willing to sign the subject's consent. 2.Pittsburgh Sleep Quality Index (PSQI) score\> 5
Exclusion criteria
1. Taking sleeping pills and melatonin 2. People suffering from mental illness 3. Pregnant or breastfeeding women 4. People who are known to be allergic to bananas 5. Have heart-related diseases 6. People with symptoms of sleep cessation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sleep monitoring | at 4 week after taking test sample | Detect the electrical activity of the heart in the potential difference between two specific points on the body surface to reflect the state of sleep |
| Insomnia Severity | at 4 week after taking test sample | The Insomnia Severity Index (ISI) will be utilized to assess insomnia severity. The minimum value is 0, the maximum value is 28. The higher the score, the worse the outcome. |
| Serotonin | at 4 week after taking test sample | Venous blood was sampled to measure concentrations of Serotonin |
| Melatonin | at 4 week after taking test sample | Collect saliva samples in the morning upon waking to measure melatonin concentration. |
| Sleeping quality | at 4 week after taking test sample | The Pittsburgh Sleep Quality Index (PSQI) will be utilized to assess sleeping quality. The minimum value is 0, the maximum value is 42. The higher the score, the worse the outcome. |
Other
| Measure | Time frame | Description |
|---|---|---|
| The change of renal function biomarkers (creatinine, BUN) of blood | at 4 week after taking test sample | Fasting venous blood was sampled to measure renal function biomarkers |
| The change of fasting blood glucose | at 4 week after taking test sample | Fasting venous blood was sampled to measure concentrations of blood glucose |
| The change of Blood lipids profiles (Total-Cholesterol, HDL-C, LDL-C, triglycerides) | at 4 week after taking test sample | Fasting venous blood was sampled to measure concentrations of Blood lipids profiles (Total-Cholesterol, HDL-C, LDL-C, triglycerides) |
| The change of liver function biomarkers (AST, ALT) of blood | at 4 week after taking test sample | Fasting venous blood was sampled to measure liver function biomarkers |
Countries
Taiwan
Outcome results
None listed