Exercise Addiction
Conditions
Brief summary
The main purpose of the present study is to determine the effects of acute and short-term (14 days) ginseng combined with branch chained amino acids supplementation on endurance exercise performance and the ability of anti-fatigue. In addition, this study also measured the performance of continuous attention during recovery period to examine the effect of supplementation on central fatigue.
Detailed description
Muscle fatigue was a common problem after exercise. When fatigue occured, body functions were affected and changed. Changbai Mountain ginseng had higher anti-fatigue substances than general commercial ginseng. And recent studies had showed that the supplementation of branched chain amino acids (BCAA), including leucine, isoleucine and valine, can increase attention and reduce fatigue. However, its effect on Changbai Mountain ginseng combined with BCAA was still unclear. Subjects were allocated to Gojinsen® drinks and placebo group (1:1 ratio) for 14 days, and then examined by maximal oxygen consumption, time to exhaustion, rating of perceived exertion (RPE), oxygen saturation (SPO2) , blood lactate concentration, and continuous attention performance test (CPT II). The Gojinsen® group significant increased maximal oxygen consumption, time to exhaustion, and attention compared to placebo group. Moreover, the Gojinsen® group significant decreased lactate concentration and fatigue compared to placebo group. By this study, Gojinsen® drinks did not showed absolute anti-fatigue effect but provided the objective evidence of fatigue-related measurement and the therapeutic potential for people suffering from exercise fatigue.
Interventions
DIETARY_SUPPLEMENTPlacebo
consume 1 sachet per day for 14 day
DIETARY_SUPPLEMENTGojinsen® drinks
consume 1 sachet per day for 14 day
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
1. healthy male and female adults aged 20-25 years old . 2. without heart, liver, kidney, endocrine or other major organic diseases). 3. had at least 3 months experience in performing exercise
Exclusion criteria
1\. BMI of the study subjects must be less than 25.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Endurance exercise performance testing | Execution on the 14th day | the subjects arrived to the laboratory and wore the oxygen uptake mask of energy metabolism analyzer (Sensor Medics, Vmax29, USA) to measure the subjects' oxygen uptake |
| rating of perceived exertion | Execution on the 14th day | The Rated Perceived Exertion was measured during the treadmill exercise by Bruce Protocol, a gradual increase in the speed and the slope of the treadmill every 3 minutes. |
| blood lactate | Execution on the 14th day | fingertip capillary blood was placed in automated blood lactate analyzer |
| Continuous attention performance test | Execution on the 14th day | 10 minutes after maximal exercise test, the subjects performed attention tests that used Canon continuous attention software |
Outcome results
None listed