Osteoarthritis, Knee, Patellofemoral Disorder
Conditions
Keywords
HTO, Fulkerson, Osteoarthritis
Brief summary
This study will compare Hight Tibial Osteotomy with or without Fulkerson Osteotomy performed on patients with early stages of Osteoarthritis with patellofemoral joint disorders. The purpose of this study is evaluate which type of osteotomy provides better clinical, radiological and laboratory outcomes.
Detailed description
Progression of knee cartilage degenerative changes leads to necessary total knee arthroplasty in future, which is the most popular procedure for treating OA. HTO applied at early stages of osteoarthritis allow slow down cartilage degeneration process, but the choice of performed surgery depends on surgeons personal assessment. Patellofemoral Pain Syndrome often occurs with knee arthritis. Antero-medialisation of tibial tubercle is frequent procedures for patella maltracking. So far, both, HTO and Fulkerson osteotomy was performed separately, even if patient have symptoms from patellofemoral joint and OA. The investigators believe that simultaneously surgery of HTO and fulkerson Osteotomy provides better outcomes and significantly slow down knee degeneration.
Interventions
PROCEDUREHigh Tibial Osteotomy
Surgery procedure - High Tibial Osteotomy
Sponsors
Centre of Postgraduate Medical Education
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Knee medial compartment or patellofemoral osteoarthritis in medical interview and physical examination * Confirmation of cartilage degeneration/damage and knee malalignment in radiological tests
Exclusion criteria
* no informed consent to participate in the study * age under 18 years or above 65 * multi ligament injury or single plane knee instability * another musculoskeletal disorders in lower limb * lower limb deformity requiring axis correction below 4o or above 12.5o * joints inflammatory diseases * ASA score \> II
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Biomechanics MRI | 1 year | Patellofemoral Joints Biomechanics improvement measured |
| Biomechanics X-ray | 12 weeks | Patellofemoral Joints Biomechanics improvement measured |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Tegner Lysholm | 12 weeks, | Tegner Lysholm Knee Scoring Scale |
| SF-36 | 12 weeks | The Short Form (36) Health Survey |
| KOOS | 12 weeks | Knee Injury and Osteoarthritis Outcome Score |
| Blood test | 2nd day | CRP, IL-6, CTx |
| VAS | 12 week | Pain Visual Analog Scale |
| IKDC | 12 weeks | International Knee Documentation Committee |
Countries
Poland
Contacts
Primary ContactRafał Kamiński, MD PhD
Outcome results
None listed