Skin Health
Conditions
Keywords
skin, inflammation, wrinkles, trans epithelial water loss, fish oil, LCMUFA
Brief summary
The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation and UV-damage. This pilot study will determine skin characteristics after intervention with north atlantic fish oil.
Detailed description
Women will be recruited to a placebo or fish oil group and be examined at pre- and post for skin quality parameters such as wrinkles, fine lines and trans-epithelial water loss.
Interventions
DIETARY_SUPPLEMENTPlacebo
1g corn oil capsules
DIETARY_SUPPLEMENTCeto 10
1g capsules containing oil broad spectrum marine oil from north atlantic fish
Sponsors
Møreforsking AS
Epax Norway AS
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Masking description
Interventions are given as 1g bovine capsules of equal size, weight and appearance, and provided in identical bottles with a coded label.
Intervention model description
Placebo controlled, double blind intervention study.
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy women in the age of 30-65 Able to follow the following dietary restriction for 4 months (4 weeks wash-out, 3 months intervention): * Do not take omega-3 supplements * do not take supplements containing vitamin A * do not take supplements containing collagen * try to avoid using skin products containing vitamin A * do not undergo skin treatment
Exclusion criteria
Pregnancy or breast feeding known allergy to seafood skin treatment the last 6 months planned skin treatment during the study period \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determine the change in skin quality of healthy women after supplementation with fish oil compared to corn oil | 3 months | Changes in quantitative analysis of facial inflammation, wrinkles and fine lines and skin texture will be performed using the VISIA Skin Analysis system. Measurements will be made at baseline and at end of supplementation period. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Determine the change in omega-3 index (%EPA and DHA in red blood cells) after daily intake of 4g of north atlantic fish oil compared to placebo | 3 months | Fatty acid profiles will be measured from blood samples using the Omega-quant test |
Countries
Norway
Contacts
Primary ContactDerek Tobin, PhD
Outcome results
None listed