Scorpion Stings
Conditions
Brief summary
In scorpion stings, patients mostly apply with the complaint of pain. Emergency physicians need to relieve this pain quickly.
Detailed description
Aim: In this study, the analgesic efficacy of intravenous (IV) paracetamol, IV dexketoprofen trometamol and topical lidocaine will be compared in patients presenting with pain after scorpion sting. Methods: This study is a double-blind, randomized, placebo-controlled study conducted in a tertiary emergency department. Adult patients who applied to the study with no systemic findings after scorpion sting and especially with pain will be randomly assigned to one of 4 groups: IV paracetamol, IV dexketoprofen trometamol, topical lidocaine or placebo. In order to determine the intensity of pain, Visual Analog Pain Score (VAS) will be measured at the time of admission to the emergency department, at the 30th minute and at the 60th minute. Afterwards, the VAS score changes between the groups will be compared.
Interventions
DRUGparacetamol
1000 mg intravenous paracetamol in 100 mL normal saline
50 mg intravenous dexketoprofen Trometamol in 100 mL normal saline
Application of 5 gr of 5% topical lidocaine
DRUGPlacebo
100 mL intravenous normal saline infusion+ placebo topical pomade application
Sponsors
Adiyaman University Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 and over * Scorpion sting with pain * The diagnostic criteria of Grade 1 for Scorpion sting
Exclusion criteria
* Patients who denied to give informed consent * Taking analgesic treatment (ice application or drugs etc.) in the last 6 hours * Any symptoms and findings of systemic toxicity of scorpion sting * Pregnant women * Hemodynamically unstable patients * Known allergy to drugs of the study * Patients with renal disease * The cases that passed more than 6 hours after the bite
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of the intensity of pain | 30 minutes and 60 minutes after the study drug administered | Pain intense will be measured by 100 mm visual analog scale (Zero; no pain and 100 mm; the worst pain) after 30th and 60th minutes later after the study drug administered |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse events | 60 minutes after the study drug administered | 60 minutes after the study drug administered |
| need to rescue medication | 60 minutes after the study drug administered | 60 minutes after the study drug administered |
Countries
Turkey (Türkiye)
Outcome results
None listed