Acute Coronary Syndrome
Conditions
Brief summary
This study aims to determine the relation between high homocysteine levels and increased incidence of acute coronary syndrome in young patients
Detailed description
Cross sectional study to: assess homocysteine level in young adult patients presenting with acute coronary syndrome
Interventions
DIAGNOSTIC_TESTHomocysteine level
diagnostic test
Sponsors
Sohag University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. \- The patients who presented in the hospital with chest pain consistent with acute coronary syndrome with any of the following features: 1. Electrocardiogram (ECG) changes: * ST elevation * ST depression * T wave inversion * recent left bundle branch block 2. Troponin T elevation (Norma value \< 0.06) 2- Age: -Between 18- 40 years (Group A) - Age \> 40 years (Group B)
Exclusion criteria
1. Chest pain not consistent with acute coronary syndrome 2. Chronic kidney disease (CKD) 3. Rheumatic heart disease (RHD) 4. Congenital heart disease 5. Anemia 6. Cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Coronary care unit admission with acute coronary syndrome | From date of randomization up to 1 month | Acute coronary syndrome hospitalization and cardiovascular deathes and estimated hazard ratios (HR) by use of multivariable Cox regression models |
Countries
Egypt
Outcome results
None listed