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Shortened Depression Assessment Study

Using the Long to Short Approach to Develop Rapid Depressions Scales

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05123794
Enrollment
39000
Registered
2021-11-17
Start date
2019-09-01
Completion date
2021-09-01
Last updated
2023-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

Depression Moderate, Depression Severe, Survey Methodology

Brief summary

Participants will be asked to fill out an online questionnaire about their demographics information and all 42 items from the Depression Anxiety Stress Scale (DASS-42). A series of machine learning techniques will be applied to the dataset to develop a shortened assessment using the most important demographics and DASS-42 items from the original questionnaire, to predict depression levels indicated by DASS-42.

Detailed description

Clinical depression affects 5-10% of the world population each year and is a serious mental health issue globally. There are many traditional psychological scales that assess levels of depression in adults, where their items are often redundant in the information they carry, and their scoring is not necessarily linear to the item scores. Thus, machine learning techniques can help find the redundancy in the items, as well as the nonlinear relationship between the item scores and the final prediction. Using the Depression Anxiety Stress Scale 42 (DASS-42) as the basis, participants will be asked to fill out an online questionnaire about their demographics information (age, gender, country of residence, race, etc.) and all 42 items of DASS-42 to provide a dataset for this study. Feature selection techniques such as MRMR and Gini feature importance were applied to identify the most important features in the dataset. Then, using machine learning methods such as Logistic Regression, XGBoost, and Ensemble models, models will be fitted on the most important features to develop a shortened depression scale (7-9 items consisting of demographics items and DASS items) that accurately predicted the levels of depression (as measured by the AUC, ROC and F1 scores.

Interventions

None listed

Sponsors

University of Toronto
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
Yes

Inclusion criteria

* Adults aged 18 and above * Must be able to read English * Must have access to the Internet worldwide

Exclusion criteria

* Children aged 17 and under * Persons who cannot read English * Persons that do not have access to Internet

Design outcomes

Primary

MeasureTime frameDescription
Rapid Depression Assessment Tool based on Depression Anxiety Stress Scale 42All participants completed the same assessments, which took 10-15 minutesParticipants filled out an online questionnaire about their demographic information (age, sex, and ethnicity) and all 42 items from the Depression Anxiety Stress Scale (DASS-42). Each item consists of a 4-point Likert scale from 0 to 3, where 0 means Did not apply to me at all and 3 means Applied to me very much, or most of the time. The depression score is the sum of scores for the items in the depression sub-scale. A higher score indicates a more severe level of depression symptoms. Machine learning techniques were used to develop a shortened assessment (Rapid Depression Assessment Tool) using demographics and 5 DASS-42 items from the original questionnaire, to predict severity levels of depression indicated by DASS-42. The assessment tool calculates the likelihood of moderate depression symptoms and severe depression symptoms given the responses from each item (ranging from 0 to 3). The data was collected and aggregated through a public website.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026