Drug Abuse
Conditions
Keywords
drug abuse, Cairo Teaching Hospital, elective surgery
Brief summary
Drug abusers and addicts form a challenge to the anesthetist because of the added potential risks involved in the administration of anesthesia to this subset of patients, including potential unforeseen drug-drug interactions. In this study, we aimed at screening all patients scheduled for elective orthopedic or general surgeries at the Cairo University Teaching Hospital during a set period of time for the most commonly abused drugs in Egypt.
Detailed description
All patients included in the study consented to take part in this study. Each patient was asked to answer a questionnaire and submit a urine sample in order to be screened for the most commonly abused drugs in Egypt (hashish, tramadol, benzodiazepine, and morphine). Patients were then followed up both intra and post-operatively. Values of patient vital signs, Richmond Agitation-Sedation Scale (RASS) scores as well as clinical recovery scores (CRS) were all diligently recorded and analyzed.
Interventions
DIAGNOSTIC_TESTurine analysis
Urine was then tested for evidence of substance abuse using the multi-drug screen panel dip steak ABONtm (Abon Biopharm (Hangzhou) CO., Ltd) which is a lateral flow chromatographic immunoassay . It allowed for qualitative detection of multiple drugs in a single run. This kit was chosen for its ability to detect the most commonly abused substances in Egypt, namely: opioids, benzodiazepines, hashish, and tramadol. A single coloured line at region C for of a specific drug indicated a positive result, whilst two coloured lines at both regions C and T indicated a negative result. The absence of coloured lines was an indication of the invalidity of the particular kit, and the kit was discarded.
Sponsors
Cairo University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 60 Years
Inclusion criteria
* male or female patients classified as American Society of Anaesthesiology (ASA) I or II patients * patients between 15 and 60 years of age * patients scheduled for elective surgery.
Exclusion criteria
* emergency surgery * those with disturbed conscious levels * history of psychological illness * who refused to give consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| urine analysis | THREE MONTHS | multi-drug screen panel dip steak (Abon Biopharm (Hangzhou) , Ltd) |
Countries
Egypt
Outcome results
None listed