Small Intestinal Bacterial Overgrowth
Conditions
Brief summary
Lactulose HMBT and Glucose HMBT are simple non-invasive tests to assess whether imbalances in gut bacteria may be contributing to troublesome tummy symptoms. These imbalances in gut bacteria include small intestinal bacterial overgrowth (SIBO) and excessive methane production. Recently there has been a lot of work to done by experts in the field, to ensure that performance and interpretation of these tests are standardised, to help improve the clinical utility of these investigations. Although there is a lot of information currently available demonstrating the risk factors and symptoms associated with these conditions, there is a lack of data demonstrating the factors that might lead to a positive test according to these new parameters. This study aims to collect data on symptoms and medical history, in patients referred for lactulose and glucose HMBT in order further improve the effectiveness of this test in the future.
Interventions
OTHERQuestionnaire
The HMBT-Q is a 26-item questionnaire, split into four main sections: food related symptoms; general digestive symptoms; extra-intestinal symptoms and co-morbidities and Medication and onset.
Sponsors
The Functional Gut Clinic
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Inclusion criteria
1. Participant is referred for and able to complete a postal Lactulose or Glucose HMBT according to protocol with The Functional Gut Clinic 2. Participant has capacity to understand written English 3. Participant can communicate well with the Investigator and to comply with the requirements for the entire study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determine positive predictive symptoms for SIBO positive participants determined by HMBT | At same time as breath test | Using the HMBTQ |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Determine positive predictive symptoms for excessive methane positive participants determined by HMBT | At same time as the breath test | Using the HMBTQ |
| Determine the frequency of recognised and potential risk factors in SIBO positive participants | At the same time as the breath test | Using the HMBTQ |
| Determine the frequency of recognised and potential risk factors in excessive methane positive participants | At the same time as the breath test | Using the HMBTQ |
Countries
United Kingdom
Outcome results
None listed