Vitiligo
Conditions
Brief summary
Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients with Non-segmental Vitiligo before and after phototherapy
Detailed description
This prospective study will include 30 patients with NSV, attending the Outpatient Clinics of Dermatology at Sohag University Hospitals, as well as 30 normal volunteers as control. This study will be submitted for approval by Research and Ethical committees at Sohag Faculty of Medicine. An informed written consent will be obtained from each subject prior to participation in the study after full explanation of the procedure.
Interventions
DIAGNOSTIC_TESTInterleukin-15 and Interleukin-22
Serum Interleukin-15 and Interleukin-22 in non segmental vitiligo
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* • Patients suffering from non segmental vitiligo. * Patients not on medical treatment or phototherapy for vitiligo in the last 3 months.
Exclusion criteria
* • Patients with systemic or cutaneous inflammatory disorders. * Patients on treatment for vitiligo in last 3 months. * Pregnant and lactating patients. * Patients with history of diabetes. * Patients with history of autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of Serum Interleukin-15 and Interleukin-22 Levels | 3 months | 3 ml venous blood will be obtained from participante using commerciall available double antibody sandwich enzyme-linked immunosorbent assay (ELISA) kits to evaluate 1. Serum IL15 level . 2. Serum IL22 level. 3 ml venous blood will be obtained from participante using commerciall available double antibody sandwich enzyme-linked immunosorbent assay (ELISA) kits to evaluate 1\. Serum IL15 level . 2. Serum IL22 level. |
Outcome results
None listed