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Investigation of Genetic Disease Marker Associated With Spontaneous Haemorrhagic Stroke Complicating Severe Pre-eclampsia in Pregnancy

Preventive and Personalized Medicine (2021-2023)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05121415
Enrollment
100
Registered
2021-11-16
Start date
2021-10-23
Completion date
2023-01-20
Last updated
2023-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eclampsia, Hemorrhagic Stroke

Keywords

SNP

Brief summary

To search for a genetic marker of hemorrhagic stroke complicating severe eclampsia, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with hemorrhagic stroke and normal control will be performed.

Detailed description

Detailed Description: Unrelated Korean subjects who have Spontaneous hemorrhagic stroke complicating severe eclampsia in pregnancy were recruited in the current study. Genotyping for various SNP associated due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with hemorrhagic stroke and normal control subjects free of hemorrhagic stroke

Interventions

SNP analysis of the DNA obtained from peripheral blood sample

Sponsors

Asfendiyarov Kazakh National Medical University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years

Inclusion criteria

-patients with hemorrhagic stroke complicating severe eclampsia in pregnancy

Exclusion criteria

patients without hemorrhagic stroke complicating severe eclampsia in pregnancy

Design outcomes

Primary

MeasureTime frame
genotyping for the SNP associated with hemorrhagic stroke complicating severe eclampsia in pregnancy1 year

Countries

Kazakhstan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026