Fertility Preservation in Transgender Persons: a Retrospective Look

Fertility Preservation in Transgender Persons: a Retrospective Look At the Decision and a Survey of the Desire for Children.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05120245

Enrollment

Registered

2021-11-15

Start date

2021-07-08

Completion date

2023-06-30

Last updated

2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility Preservation in Transgender Persons

Brief summary

Patients in this study will be asked how they feel about the decision to freeze gametes, using a validated questionnaire. In addition, a number of questions with free text fields will be included in the questionnaire to write down any reasons for their satisfaction or regret. In a second part, the intention to use the frozen material will be assessed. We focus on techniques with real perspectives (e.g. cryopreservation of oocytes and sperm cells) and not on techniques that are more experimental for later use (cryopreservation of ovarian and testicular tissue).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Dutch speaking * Sperm or oocyte preservation between june 2015 and june 2020. Survey in 2021

Exclusion criteria

* Ovarian and testicular tissue cryopreservation

Design outcomes

Primary

Measure	Time frame	Description
Transgender people's retrospective view of the decision	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)	Study of transgender persons' retrospective evaluation of the decision to freeze egg or sperm cells prior to gender-confirming hormonal or surgical treatment in transition
Satisfaction/ regret about the decision	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)	Survey on the reasons for satisfaction/ regret regarding the decision to freeze egg cells or sperm cells prior to gender-confirming hormonal or surgical treatment in the context of transition
Intention	fertility preservation between june 2015 and june 2020 (5 years). Survey in 2021 (up to 7 years after preservation)	Examination of the intention to use the frozen egg cells or sperm cells to fulfil a desire to have children

Countries

Belgium

Outcome results