Evaluation of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in a Large Cohort

Prevalence of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in Occitania

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05119478

Acronym

CYPPOT

Enrollment

594

Registered

2021-11-15

Start date

2021-10-01

Completion date

2022-04-01

Last updated

2021-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis

Keywords

Cypress, gibberellin-regulated protein, peach, potato, rhinitis

Brief summary

The aim of the study will be to investigate the prevalence of of sensitization to peach and/or cypress in potato sensitized patients, based on the collection of medical data from patient records consulting in the Allergy Unit of the Arnaud de Villeneuve Hospital. Some Gibberellin-regulated protein (GRP) in fruits and pollens have been identified as allergen, and peach GRP (peamaclein) has recently emerged as a relevant food allergen in cypress pollen-hypersensitive patients. Multiple fruit allergies might be related to cross-reactivity between GRPs. Peamaclein shares 82% identity with snakin-1 from potato. Thus, because of this hight homology the investigators want to determine the prevalence of cosensitization between these 3 allergens potato, peach and cypress.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

2 Years to 99 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients evaluated at the Montpellier University Hospital, Allergy Unit * children and adult with positive skin prick test to potato from february 2013 to december 2015

Exclusion criteria

* Patients under legal protection * Patients under guardianship or under curatorship * Patients not capable of understanding French

Design outcomes

Primary

Measure	Time frame	Description
Rate of sensitization to peach and/or cypress in potato-sensitized patients	day 1	Rate of sensitization to peach and/or cypress in potato-sensitized patients

Secondary

Measure	Time frame	Description
Rate of of sensitization to peach and/or cypress in potato-sensitized patients	day 1	Rate of sensitization to peach and/or cypress in potato-sensitized patients (cypress pollen-induced allergic rhinitis or food allergy to peach)

Countries

France

Contacts

Primary ContactDavide CAIMMI, MD

davide.caimmi@gmail.com467336112

Backup ContactEvangéline CLARK, doctor

e-clark@chu-montpellier.fr467336107

Outcome results