Optical Coherence Tomography Angiography and Pseudophakic Cystoid Edema

Peripapillary Vascular Density in the Pathogenesis of Pseudophakic Cystoid Edema

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05117411

Enrollment

Registered

2021-11-11

Start date

2016-01-01

Completion date

2020-12-30

Last updated

2021-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pseudophakic Cystoid Macular Edema

Brief summary

This study evaluates the retinal vascular features in macula and papillary regions in patients affected by pseudophakic cystoid edema using optical coherence tomography angiography

Detailed description

Pseudophakic cystoid edema represents one of the most common causes of poor visual outcome following cataratta surgery. It is still source of debate the pathogenesis of Pseudophakic cystoid edema. Optical coherence tomography angiography represents a novel and non-invasive diagnostic technique that allows a detailed analysis of retinal vascular features. The study evaluates retrospectively the changes in optical coherence tomography angiography parameters at baseline and after three monthly after surgery.

Interventions

DIAGNOSTIC_TESTOCTA and pseudophakin cystoid edema

Patients underwent OCT angiografia after cataract surgery

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

60 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* age older than 60 years * diagnosis of pseudophakic cystoid macular oedema * treatment-naïve for pseudophakic cystoid macular oedema * absence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)

Exclusion criteria

* age younger than 60 years * No diagnosis of pseudophakic cystoid macular oedema * previous treatment for pseudophakic cystoid macular oedema * presence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)

Design outcomes

Primary

Measure	Time frame	Description
OCTA and pseudophakic cystoid macular oedema	3 months	The parameters analyzed by OCTA three months after surgery are: Vessel density (%) of superficial capillary plexus, deep capillary plexus, coriocapillary plexus in macular region Vessel density (%) of radial peripapillary capillary plexus in papilllary region

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026