Comparison of Care Practices, Mortality and Morbidity of Very Preterm Infants Between Two Tertiary Centers in Northwest and South of China

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05116670

Enrollment

807

Registered

2021-11-11

Start date

2021-10-15

Completion date

2021-12-31

Last updated

2022-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morality, Morbidity;Newborn, Very Preterm Maturity of Infant

Keywords

care practices, mortality, morbidity, very preterm infant, comparison

Brief summary

Care practices, mortality and morbidity of very premature infants from two different tertiary centers were collected and compared, in order to discover areas for improvement where these two newborn centers can learn from each other.

Detailed description

This retrospective cohort study was conducted in two hospitals,Qinghai Red Cross Hospital and Jinan University affiliated Shenzhen Baoan Women's and Children's Hospital.Very premature infants born with a gestational age between 22+0 - 31+6 weeks admitted to both centers during 3 years from January 1, 2018 to December 31, 2020 were studied. In both centers, data including maternal characteristics, neonatal characteristics, obstetric practices, delivery room practices, and neonatal outcomes, were collected by data abstractors in each NICU. Anonymous data was transferred to Shenzhen and analyses were performed at the newborn center of SZH.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Days to 28 Days

Inclusion criteria

* Very premature infants born with a gestational age between 22+0 - 31+6 weeks； * Admitted to both centers during 3 years from January 1, 2018 to December 31, 2020.

Exclusion criteria

* Infants not born at QHH or SZH (out born); * Infants who had major congenital anomalies; * Infants admitted after 7 days of life.

Design outcomes

Primary

Measure	Time frame	Description
mortality	Jan 1,2018 - Dec 31,2020	death during hospitalisation and death after withdrawing treatment
Major morbidity	Jan 1,2018 - Dec 31,2020	severe neurological injury, moderate to severe BPD, NEC or severe ROP

Countries

China

Outcome results