High Altitude
Conditions
Brief summary
The now widely used reference interval for pulse oxygen saturation of the neonate after 24 hours of birth has been developed relying on data from low altitude.It is not suitable for neonates at high altitude. At present, no reference interval has been established at high altitude, and the existing studies have many limitations. So this study was designed.
Detailed description
Knowledge of the reference interval of pulse oxygen saturation (SpO2) in neonates is crucial for accurate identification of neonatal hypoxemia. The now widely used standard was derived from low altitude data, which is not suitable neonates at high altitude. At present, many scholars have paid attention to this problem. But, previous studies still have some limitations. For example, they often only focus on a specific altitude. However, with the increase of altitude, the pulse oxygen saturation decreases in a curve, so their study results are only suitable for this specific altitude and can not be widely used.
Interventions
OTHERno intervention
It's only observational study. No interventions.
Sponsors
Affiliated Hospital of Qinghai University
Qinghai Red Cross Hospital
Qinghai Women and Children's Hospital
Geermu People's Hospital
Yushu Prefecture People's Hospital
Guoluo Tibetan Autonomous Prefecture People's Hospital
Nanjing Medical University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
24 Hours to 28 Days
Healthy volunteers
Yes
Inclusion criteria
* Healthy singleton term infants with no clinical signs and symptoms (e.g., cyanosis, respiratory distress, heart murmur, etc.).
Exclusion criteria
* 1\. Low birth weight (\< 2500 g). 2. Need for oxygen. 3.1 or 5 minute Apgar score \< 7. 4. Referred to the neonatal intensive care unit or neonatology department for various reasons. 5. Neonates discharged within 24 hours of birth. 6. Neonates diagnosed with congenital diseases in utero. 7. Refusal of consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pulse oxygen saturation of healthy neonates at high altitude. | 24 hours after birth | Pulse oxygen saturation of the right hand and any foot of healthy neonates born at high altitude will be measured 24 hours after birth. According to the normality of the results, the distribution range will be described by mean ± standard deviation or range interquartile. Altitude level: ≥ 2000m. |
Countries
China
Contacts
Primary ContactZhangbin Yu, PHD
Outcome results
None listed