Sarcopenia
Conditions
Keywords
sarcopenia, ultrasound, aged, hospitalized
Brief summary
Observational prospective study in older adults admitted to an Acute Geriatric Unit, in which sarcopenia will be evaluated by ultrasound in the anterior rectus femoris muscle.
Detailed description
The main objective of the study is to estimate, by means of portable ultrasound, parameters of muscle quantity and quality (anterior rectus femoris muscle area, width and echostructure ) in older adults hospitalized in Acute Geriatric Units for medical reasons.
Interventions
DIAGNOSTIC_TESTmuscle ultrasound
All participants will undergo a muscle ultrasound on admission and at discharge
Sponsors
Hospital Universitario Getafe
Hospital Infanta Sofia
Hospital Universitario Infanta Leonor
Hospital Universitario La Paz
Puerta de Hierro University Hospital
Hospital Virgen del Valle de Toledo
Pedro Abizanda
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
69 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over 69 years of age. * Hospitalization for a medical cause in Acute Geriatric Units. * Holden's Functional Ambulation Classification Scale at level 1 or higher. * Informed consent signed by the patient or legal representative.
Exclusion criteria
* Terminal condition or life expectancy of less than 6 months. * Impossibility or refusal to undergo muscle ultrasound. * Refusal for follow-up * Severe dementia stage Global Deteriorating Scale: 7 * Impossibility in the opinion of the investigators to complete the necessary data for the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of sarcopenia on admission | 72 hours | Prevalence of sarcopenia on admission. A prevalent case of sarcopenia will be considered if a patient fulfills the EWGSOP2 at admission |
| Incidence of sarcopenia between admission and discharge | 15 days | An incident case of sarcopenia will be considered if a patient not fulfilling EWGSOP2 diagnostic criteria on admission, will meet diagnostic criteria at discharge of sarcopenia at discharge (diagnosis will be considered as a dichotomous variable -yes/no-). |
| Muscle mass (the anterior rectus femoris muscle) | 15 days | The evolution of muscle mass between admission and discharge will be assessed by ultrasound |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ADL (Activities of Daily Living) questionnaire | 3 months | the ADL questionnaire will also be performed on admission, at discharge, and at 3 months. |
| SPPB score (SHORT PHYSICAL PERFORMANCE BATTERY score) | 15 days | Short Physical Performance Battery (SPPB): score range 0-12, higher score means a better outcome |
| Mortality | 3 months | Mortality will be measured with vital status at 3 months. |
| Minimal nutritional assessment (MNA-SF) score | 72 hours | The mini-nutritional assessment - short form is a simple, non - invasive and validated scale for the detection of malnutrition in older adults. It takes into account the patient's loss of appetite, weight loss, motor skills, recent health status, neuropsychological disorders. The maximum score of the MNA-SF is 14: Greater than or equal to 11: normal nutritional status. Between 8 and 11: risk of malnutrition. Less than 8: malnutrition. |
| Readmission(s) after index hospitalization | 3 months | Readmission(s) after index hospitalization, Dichotomous outcome (yes/no) |
| Emergency department (ED) visit(s) | 3 months | ED visit(s) after index hospitalization, Dichotomous outcome (yes/no) |
| Length of stay, days | 15 days | Day of admission to day of discharge |
| Hand grip strength | 15 days | Using a hand-held dynamometer |
| 4-meter walking speed test | 15 days | The evolution of the value of the 4-meter walking speed test between admission and discharge will be assessed. |
Countries
Spain
Outcome results
None listed