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Association of Cognition With Functional Mobility in People With Alzheimer's Disease

Association of Cognition With Functional Mobility in People With Alzheimer's Disease

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05113732
Enrollment
64
Registered
2021-11-09
Start date
2021-11-01
Completion date
2022-05-01
Last updated
2021-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer Dementia, Alzheimer's Disease, Dementia, Alzheimer Type

Brief summary

This study aimed to investigate relationship between cognitive function and functional mobility in Alzheimer's disease.

Detailed description

Our hypothesis is that the decrease in cognitive function in individuals with Alzheimer's disease is associated with the level of functional mobility. Sociodemographic information of participants will be recorded. Cognition will assessed with Montreal Cognitive Assessment (MoCA), global score and MoCA's visuospatial executive functions, naming, attention, language, abstract thinking, delayed recall, orientation sub-scores will recorded. Functional mobility will assessed Timed Up and Go Test and 5 Times Sit&Stand Test.

Interventions

None listed

Sponsors

Istanbul University - Cerrahpasa
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Diagnosed with Alzheimer's disease according to the National Institute of --Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease (NINCDS-ADRDA) criteria, * Over 65 years old, * Cases who could understand the instructions given in Turkish were included in the study, * Having ambulation skill independently or with walking aid.

Exclusion criteria

* Dementia with Lewy bodies, frontotemporal dementia and one of the other types of dementia, * Having a pulmonary, neurological, musculoskeletal or rheumatological disease that may prevent exercise, * Unstable medical condition (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.), * Subjects with visual or auditory deficits or behavioral problems that would make communication difficult were not included in the study.

Design outcomes

Primary

MeasureTime frameDescription
Montreal Cognitive Assesment (MoCA)BaselineMoCA assesses cognitive skills such as visuospatial / executive functioning, object naming, memory, attention, language, abstraction, orientation. Higher scores reflect the better performance.
Timed Up and Go TestBaselineTimed Up and Go Test measures the level of functional mobility skills and, assess fall risk and balance. The time elapsed between standing up from the sitting position, walking the distance of 3 meters, coming back and sitting back on the chair is recorded. The shorter time reflect the better performance.
5 Time Sit to Stand TestBaseline5 Time Sit to Stand Test measures the level of functional mobility skills and, assess fall risk and lower extremity strength. The test measures the time taken to stand five times from a sitting position as quickly as possible. The shorter time reflect the better performance.

Countries

Turkey (Türkiye)

Contacts

Primary ContactKübra Nur Menengiç, MSc
kmenengic@gmail.com+90 05054400987
Backup Contactİpek Yeldan, PhD
ipek.yeldan@iuc.edu.tr+90 0 (212) 866 37 00

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026