Post-prandial Glycemia
Conditions
Brief summary
The aim of this study is to test the effects of Mulberry leaf extract on glucose response of a standardized complete meal when taken just before or when mixed with the meal.
Interventions
DIETARY_SUPPLEMENTMulberry leaf extract
Oral administration
DIETARY_SUPPLEMENTWater
Oral administration
Sponsors
Société des Produits Nestlé (SPN)
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Male and female participants * Healthy status (based on anamnesis) * Age between 18 and 45 years * BMI between 20 and 29.9 kg/m2 * Ability to understand and sign an informed consent form
Exclusion criteria
* Pregnant or lactating women * Major medical/surgical event in the last 3 months potentially interfering with study procedures and assessments * Known food allergy and intolerance to test product * Medically known cutaneous hypersensitivity to adhesives and plasters * Alcohol intake higher than 2 servings per day. A serving is 0.4 dl of strong alcohols, 1 dl of red or white wine, or 3 dl of beer. Smokers Volunteer who cannot be expected to comply with the protocol Subject having a hierarchical link with the research team members.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-prandial glucose | Hour 0 to hour 3 after standard meal consumption | Incremental area under the curve |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| C max glucose | Hour 0 to hour 3 after standard meal consumption | Incremental C max |
| T max glucose | Hour 0 to hour 3 after standard meal consumption | Incremental T max |
Countries
Switzerland
Outcome results
None listed