Symfony Intraocular Lens Retrospective Chart Review

Experience With Symfony Extended Depth of Focus (EDOF) IOL: A Retrospective Chart Review

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05111106

Enrollment

463

Registered

2021-11-08

Start date

2016-10-05

Completion date

2018-12-31

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Keywords

Cataract surgery, Glaucoma, Retinopathy, Intraocular Lens

Brief summary

Retrospective chart review of patients with pre-existing ocular pathology who underwent cataract surgery with implantation of the Symfony IOL.

Detailed description

This was a retrospective chart review conducted at a single US clinical site. Chart review was conducted by John Odette, MD and research assistants. Eligible charts were identified via a clinic database search of cataract surgeries with IOL implantation of the Symfony IOL during the stated date range. Eligible charts included those of patients 18 to 90 years of age who underwent Femto Laser Assisted Cataract Surgery (FLACS) with implantation of a Symfony IOL. Charts were excluded for lack of postoperative follow-up or if Symfony IOL was not implanted. All qualifying patient charts were examined and further classified into 2 groups: (1) eyes with glaucoma; and 2) eyes without glaucoma. Visual acuity was evaluated for patients who underwent cataract surgery with implantation of the Symfony IOL from 09/1/2016 to 05/31/2018. Postoperative evaluations at Month 2 included mean monocular uncorrected visual acuity at near (UNVA) at 40 cm, far distance (UDVA) at 20 ft, and with best correction (CDVA). Outcomes were also compared for toric IOLs versus spherical IOL.

Interventions

DEVICESymfony IOL

Implantation of Intraocular lens with extended depth of focus.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* :Phacoemulsification cataract surgery with a Symfony IOL.

Exclusion criteria

* : Eyes not implanted with a Symfony IOL or unstable refractive results at final post-operative visit

Design outcomes

Primary

Measure	Time frame	Description
Monocular uncorrected near visual acuity	2 months	handheld near card (Jaeger scale)

Secondary

Measure	Time frame	Description
Monocular best corrected distance visual acuity	2 months	Snellen Chart at 20 feet

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026