Diabetes Mellitus
Conditions
Keywords
DM
Brief summary
Recently, HIIT has been recommended by the American diabetes association for type 2 diabetes. The high-volume HIIT has been studied extensively in patients with type 2 diabetes, however, little is known about the effectiveness of low-volume HIIT regarding target glycemic or lipid control in these patients. Therefore, the purpose of this study is to compare between two subtypes of HIIT (i.e. the low-volume HIIT versus the high-volume HIIT) with respect to exercise-induced changes in blood glucose, lipid profile and anthropometry in patients with type 2 diabetes mellitus. Statement of the Problem Is there any difference between the effect of high-volume and the low-volume high intensity interval training on glycemic and lipids control in type 2 diabetes? Purpose of the study: To assess the effect of the high-volume versus the low-volume high intensity interval training on glycemic and blood lipids control in type 2 diabetes. Null Hypothesis: There will be no difference between the effect of the high-volume versus the low-volume high intensity interval training on glycemic and blood lipids control in type 2 diabetes.
Interventions
OTHERThe high-volume HIIT
patients will undergo a warm up at 65%-70% of HRpeak for 5 minutes, and then they will walk on a treadmill for 4 intervals of 4 min each at an intensity corresponding to 85%-90% of HRpeak with 3 min active recovery interval interval in between at 65%-75% of HRpeak. Finally, a 3-min cool-down period will be permitted. The speed and the inclination of the treadmill will be adjusted between intervals to ensure that all patients are exercising at the desired target heart rate monitored by Pulse Oximeter.
OTHERThe low-volume HIIT
Each session will start with a 5-minute warm up at 65-70% of peak HR. Then they will walk on a treadmill for 4 intervals of 2 min each at an intensity corresponding to 85%-90% of HRpeak with three intervals of active recovery in between for 2 min at 65%-75% of HRpeak. Finally, a 3-min cool-down period will be permitted.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
35 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
1. Type II diabetes mellitus diagnosed by a physician as having HbA 1c of > 6.5%. 2. An established diagnosis of T2DM for at least 1year and less than 5 years. 3. Women patients. 4. Age between 35 to 45 years old. 5. Systolic Blood pressure less than or equal 130 mmHg. 6. Obese patients (BMI is between 30 and 39.9 kg/m 2 ) 7. Patients with HbA 1c of 7-9%. 8. A self-reported sedentary lifestyle. 9. Patients receiving oral hypoglycemic medications described by the physician 10. Patients with hyperlipidemia.
Exclusion criteria
1. Patients with Cardiac diseases. 2. Patients with glaucoma. 3. Patients with diabetic complications (Diabetic foot, retinopathy, nephropathy, and diabetic peripheral neuropathy). 4. Musculoskeletal or neurological limitations to physical exercise. 5. Pregnancy 6. Patients under insulin therapy 7. Patients with poorly controlled DM (HbA1c > 9%) 8. Bronchial asthma and chronic obstructive pulmonary disease. 9. Smokers. 10. Morbidly obese BMI ≥ 40 kg/m 2 11. Males. 11\. Systolic Blood pressure more than 130 mmHg. 12. Anemia ( hemoglobin < 12 g/dL) 13. Osteopenia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| body mass index | 12 weeks | change in body mass index |
| waist circumference | 12 weeks | change in waist circumference |
| waist/hip ratio | 12 weeks | change in waist/hip ratio |
| Systolic and diastolic blood pressure | 12 weeks | change in Systolic and diastolic blood pressure |
| HbA1c | 12 weeks | change in HbA1c |
| fasting & 2-h post prandial blood glucose | 12 weeks | change in fasting & 2-h post prandial blood glucose |
| fasting lipid profile | 12 weeks | change in fasting lipid profile |
Countries
Egypt
Outcome results
None listed