Obstructive Sleep Apnea, Reflux, Laryngopharyngeal
Conditions
Brief summary
The aim of the study is to find, using validated and efficient tools, a laryngopharyngeal reflux in patients receiving polysomnography for suspected obstructive sleep apnea syndrome. It is proposed to carry out simultaneously, at the Sleep Center of the Polyclinique of Poitiers (CSPP), a polysomnography, a 24-hour Restech pharyngeal pH-metry (day and night), a Peptest (in the evening and in the morning of the polysomnography), with the RSS-12 questionnaire and the RSA score.
Interventions
DIAGNOSTIC_TESTPolysomnography
A polysmnography is planned for every patients in order to evaluate the Apnea-Hypopnea Index (AHI).
DIAGNOSTIC_TESTPharyngeal ph-metry Restech
Pharyngeal ph-metry Restech over 24 hours (night and day)
PROCEDUREPeptest
Saliva sample to look for an association between pharyngolaryngeal reflux and obstructive sleep apnea syndrome
BEHAVIORALQuestionnaire RSS-12
Questionnaire with 12 items about quality of life. Score between 0 and 5.
PROCEDUREReflux Sign Assessment
RSA score about anatomy and morphology of the mouth
Sponsors
Elsan
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (\> 18 ans) * Polysomnography planned for OSA assessment * RPL known or not, suspected or not * Affiliation to a social security scheme or beneficiary of such a scheme * Patient having signed the free and informed consent
Exclusion criteria
* Minors * Smoking, alcoholism, chronic or serious disabling pathology * Medical history of upper aerodigestive tract cancer, radiotherapy * Recent infection of upper aerodigestive tract, chronic rhinosinusitis * Permanent nasal obstruction * Active allergy * Non-obstructive SAS (central) * Patient under anti-secretory treatment (IPP) during the 8 days preceding the Restech associated with the PSG * Refusal to participate in the study * Protected patients: Adults under guardianship, guardianship or other legal protection, deprived of liberty by judicial or administrative decision * Pregnant, breastfeeding or parturient * Hospitalized without consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of patients with Obstructive Sleep Apnea Syndrome diagnosed with pharyngolaryngeal reflux. | 3 months | the diagnosis of OSA is posed by the PSG as soon as the AHI is ≥ 15 / h |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| RSS-12 score | 3 months | Positive (\>11) |
| RSA score | 3 months | Positive if \> 14 |
| Peptest | 3 months | Positive if \> 75 ng / mL |
Countries
France
Outcome results
None listed