Influencing Factors on Gait Variability in PD

Influencing Factors and Improving Strategy on Gait Variability in People With Parkinson's Disease

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05109897

Enrollment

100

Registered

2021-11-05

Start date

2021-11-01

Completion date

2022-12-31

Last updated

2021-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease

Keywords

Parkinson's disease, Gait variability

Brief summary

The principal motor features of Parkinson's disease (PD) include rigidity, tremor, bradykinesia, and postural instability. These motor deficits might cause gait dysfunction including reduced gait velocity, stride length, arm swing, and increased gait variability. Among these, increase in gait variability increased fall risk and served as a marker of disease progression. Previous studies reported that some factors might influence gait variability. However, which one contributes most has not yet been verified. Therefore, the purpose of the present study is to identify the more related influencing factors on gait variability in people with PD.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

40 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Idiopathic PD * Hoehn and Yahr stages I through III * Ability to stand and walk 5 m independently with or without any walking aids * Stable medication usage

Exclusion criteria

* Unstable medical conditions * Any neurological, cardiopulmonary or orthopedic problem/diseases that may interfere with participating the study

Design outcomes

Primary

Measure	Time frame	Description
Gait variability	10 minutes	Using GAITRite system to measure coefficient of variation
Walking speed	10 minutes	Using GAITRite system to evaluate
Sensory organization test	20 minutes	Using NeuroCom Smart Balance Master to measure
Part III of the Unified Parkinson's Disease Rating Scale	20 minutes	The score ranged from 0 to 72. Higher scores show increased severity.
Tinetti Balance Scale	10 minutes	The score ranged from 0 to 28. Higher scores show better balance.
New freezing of gait questionnaire	15 minutes	The score ranged from 0 to 29. Higher scores show increased severity in freezing of gait.
Montreal Cognitive Assessment	20 minutes	The score ranged from 0 to 30. Higher scores show better cognitive function.

Countries

Taiwan

Contacts

Primary ContactYea-Ru Yang, PhD

yryang@nycu.edu.tw886228267279

Outcome results