Short-term Outcomes of Transanal Total Mesorectal Excision With Structured Training Curriculums in China

Short-term Outcomes of Transanal Total Mesorectal Excision With Structured Training Curriculums in China: Retrospective Study of the First Twenty-five Cases in Seven High-volume Centers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05108753

Enrollment

175

Registered

2021-11-05

Start date

2017-02-01

Completion date

2021-09-30

Last updated

2021-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Cancer

Brief summary

Transanal total mesorectal excision (TaTME) is an alternative for mid-low rectal cancer. In China, this procedure has been performed in high-volume centers with structured training curriculums. This study aimed to evaluate the short-term outcomes during the initial implementation of the TaTME procedure in high-volume centers who followed structured training curriculums in China.

Interventions

OTHERProcedure/Surgery

Transanal Total Mesorectal Excision

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Age between 18 and 75 years * American Society of Anesthesiologists (ASA) score I to III * A biopsy proven histological diagnosis of rectal carcinoma * Undergoing transanal total mesorectal excision

Exclusion criteria

* Pregnant or lactating women * Synchronous rectal carcinoma * History of colorectal cancer or other malignant tumors * Clinical evidence of metastasis * Emergency procedure

Design outcomes

Primary

Measure	Time frame	Description
incidence of anastomotic leakage	thirty days after surgery	according to the International Rectal Cancer Study Group

Secondary

Measure	Time frame	Description
incidence of Defecation disorders	6 months after surgery	A Wexner score \>10 indicated the existence of defecation dysfunction
incidence of positive distal resection margin	30 days after surgery	A positive distal resection margin (DRM) was diagnosed with the presence of tumor cells within 1mm from the DRM
incidence of positivecircumferential resection margin	30 days after surgery	The positive circumferential resection margin (CRM) was defined as the presence of tumor cells within 1 mm from the CRM

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026