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OSV-IRM - Volunteer MRI Sequence Optimization

OSV-IRM - Volunteer MRI Sequence Optimization

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05107232
Acronym
OSV-IRM
Enrollment
600
Registered
2021-11-04
Start date
2021-11-04
Completion date
2027-12-31
Last updated
2021-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MRI

Brief summary

Optimization of magnetic resonance imaging (MRI) protocols on healthy volunteers and voluntary patients. In MRI, a large number of technical parameters (sequence, parameters in sequence, antenna, reconstruction method, etc.) can be changed to optimize the diagnostic quality of the exam. Some optimizations can be performed on participants healthy volunteers, others need to be carried out on images pathological and acquired in voluntary patients.

Detailed description

An inclusion visit is planned to verify the criteria for selection, then an imaging visit to perform the MRI examination. The imaging visit can take place at the end of the inclusion visit and until the following 15 days. For healthy volunteers, the visits are organized according to their availability. For patients, on the other hand, participation in the research will depend on the programming of the MRI within the framework care. This is a single-center prospective study carried out at two sites in the Rennes University Hospital.

Interventions

OTHERMRI

MRI

Sponsors

Rennes University Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
6 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Criteria common to all participants: * Minor or major subject * Affiliated, himself or through his parents if he is a minor, to a a social security scheme * Having given their free, informed and written consent, and/or which the free, informed and written consent of the holder(s) parental authority has been obtained for minors Specific criteria for healthy volunteers: o No medical or surgical history related to the anatomical area(s) scanned Specific criteria for voluntary patients: o Indication for an MRI exam as part of its management

Exclusion criteria

* \- Contraindication to an MRI (pacemaker or pacemaker, neurostimulator, intra-orbital metal body, vascular clip ferromagnetic) * Pregnancy * Legal protection measure for adults in progress (safeguard of justice, guardianship, curatorship) or subject deprived of liberty

Design outcomes

Primary

MeasureTime frameDescription
Quality of MRI signal15 daysThe quality of the images, maps or signals collected will be compared to standard acquisitions. This evaluation will be done by statistical comparison of visual qualitative criteria by expert radiologists or on quantitative criteria drawn from analyzes computing data obtained by processing experts images (signal-to-noise ratio, contrast-to-noise ratio, blur level, mutual information, co-location of regions highlighted by different techniques, etc.).

Countries

France

Contacts

Primary ContactBlandine Gautier
blandine.gautier@chu-rennes.fr299282591
Backup ContactJean-Christophe Ferre, Pr

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026