Non-Alcoholic Fatty Liver Disease
Conditions
Brief summary
Early detection of renal impairment in patients with non-alcoholic fatty liver disease and its correlation with serum Adiponectin level.
Detailed description
Detection of serum Adiponectin by ELISA technique using (EIA-3418) KIT, DRG international inc., USA
Interventions
DIAGNOSTIC_TESTserum Adiponectin
serum adiponectin as early marker for renal impairment. Adiponectin is a recently identified adipose tissue-derived protein (adipocytokine) with important metabolic ,antiinflammatory, anti-atherogenic, and reactive oxygen species protective actions.
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patients with fatty liver aged from 18 to 60 yrs either diabetic or not . * Patient with normal echogenic kidney in ultrasound and eGFR more than 60 mL/min/1.73m2. * The Control group are completely healthy subjects without any systemic or liver and kidney affection
Exclusion criteria
* Patients less than 18 yrs & more than 60 yrs . * All patients having any other causes of renal and hepatic disease rather than Diabetes and having any other systemic problem.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlate serum Adiponectin level with renal impairment in non-alcoholic fatty liver disease. | baseline | measure level of serum Adiponectin in non-alcoholic fatty liver patients to detect early renal impairment. |
Contacts
Primary ContactHend Abdelrheem, Resident
Outcome results
None listed