Essential Hypertension
Conditions
Brief summary
Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction
Interventions
Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction
Sponsors
Shenzhen People's Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* It meets the diagnostic criteria of acute ST segment elevation myocardial infarction: ischemic chest pain lasts for more than 30 minutes and can not be relieved by taking nitroglycerin; ST segment elevation of ECG with two or more adjacent leads, limb lead ≥ 1mm, chest lead ≥ 2mm; Or new left bundle branch block; The serum markers of myocardial necrosis increased at least twice the normal value * Acute myocardial infarction was confirmed by coronary angiography * The clinical and angiographic data were complete * Direct PCI was performed within 12 hours after onset
Exclusion criteria
* Those who do not cooperate in the inspection, have poor compliance and cannot guarantee the completion of the test * Conscious disorder, obvious intellectual disorder and mental disorder * With metal foreign bodies, such as metal prosthesis, intraocular metal foreign bodies, intracranial aneurysm clamp, etc * People with claustrophobia * Had a history of myocardial infarction, PCI and coronary artery bypass grafting * Factors affecting ST segment changes of ECG: complete left bundle branch block, preexcitation syndrome, pacemaker ECG, etc
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major Adverse Cardiovascular Events | 1 weeks after baseline | The incidence of mace after 1 week of treatment |
Countries
China
Outcome results
None listed