Cerebral Tumor, Craniotomy, Dexmedetomidine, Neurophysiology, Propofol, Remifentanil, Seizures
Conditions
Brief summary
Awake craniotomy require a cooperative patient during resection neurosurgery phase. Anesthesiologist should guarantee analgesia, sedation, nausea and vomiting prevention, while maintaining normal vital parameters. Neurosurgeon could be help by Intraoperative electrocorticography to maximise lesion resection and avoiding neurologic sequelae. Propofol and remifentanyl have been largely used. Dexmedetomidine represents an alternative. However little is known about the role of dexmedetomidine on Intraoperative electrocorticography.
Interventions
DRUGPropofol
awake neurosurgery under propofol-remifentanil sedation
Sponsors
Azienda Sanitaria-Universitaria Integrata di Udine
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* PATIENTS UNDERGOING AWAKE CRANIOTOMY FOR TUMOR RESECTION (EXCLUDED E.G. SURGERY OF EPILEPSIA) * INTRAOPERATIVE MONITORING (IOM) WITH ELECTROCORTICOGRAPHY * AWAKE-AWAKE-AWAKE TECHNIQUE
Exclusion criteria
* AGE \<18 YEARS OLD * NON AWAKE-AWAKE-AWAKE TECHNIQUE * ABSENCE OF IOM
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| SEIZURE ACTIVITY | DURING TUMOR RESECTION PHASE OF THE AWAKE CRANIOTOMY | INCIDENCE OF ELECTRO-CLINICAL SEIZURE ACTIVITY IN THE TWO GROUPS DURING RESECTIVE PHASE OF AWAKE CRANIOTOMY EVALUATED WITH ELECTROCORTICOGRAPHY. |
Countries
Italy
Outcome results
None listed