Post-transition Clinical and Socio-professional Future in Adult Patients With Recurrent Multifocal Chronic Osteitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05103137

Acronym

ESPERANTO

Enrollment

Registered

2021-11-02

Start date

2020-10-08

Completion date

2020-11-10

Last updated

2021-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Recurrent Multifocal Osteomyelitis

Brief summary

Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disease in children. Studies evaluating the quality of life of patients with CRMO are small and heterogeneous. A better understanding of the impact of the disease on the quality of life of adult patients with CRMO beginning in childhood would allow better long-term management of these patients. Our study aims are to assess the clinical and socio-professional outcomes of adult patients who started CRMO at pediatric age.

Interventions

OTHERQuestionnaire

Questionnaires concerning assesment of quality of life with 3 different questionnaires ( SF36, HAQ and pre-established questionnaire for the study) during a phone interview

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult Patient with a CRMO with pediatric-onset disease (\> 18years) * Patient who was informed and agreed to participate in this study

Exclusion criteria

* Patients with Monogenic auto-inflammatory disease associated with osteolytic bone lesions (e.g. interleukin-1 receptor antagonist deficiency) * Patient with Majeed syndrome * Patient without sufficient imaging data to confirm the presence of one or more inflammatory lesions * Patients with incomplete data. * Patients placed under legal protection, guardianship or curatorship

Design outcomes

Primary

Measure	Time frame	Description
Impact of the disease on the quality of life of adult CRMO patients with pediatric-onset disease.	20 minutes	Result of the SF 36 (Short Form 36) quality of life questionnaire compared to data in the general population and other published data available in CRMO and inflammatory diseases in children. This questionnaire is composed of 36 questions which allow to calculate two scores of the quality of life of individuals: the physical composite score (SCP) and the mental composite score (SCM). The higher the score the higher the capacity. Range 0 to 100

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026