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Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions

Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions in the Presence of Hydroxyapatite, Nanohydroxyapatite and Combination of Nanohydroxyapatite and Platelet-rich Fibrin. A Clinical Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05100615
Enrollment
24
Registered
2021-10-29
Start date
2021-11-30
Completion date
2022-05-31
Last updated
2021-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effects of the Elements

Brief summary

recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for month, three months and six months for the healing of periapical bone

Interventions

PROCEDUREsurgery

applying the graft inside bony defect after surgery

Sponsors

Minia University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* The patient will be in range of 20-45 years of age at the time of treatment, having periapical lesions starting from 5mm or more in diameter related to failed endodontically treated single canaled teeth.

Exclusion criteria

* Any systemic debilitating disease such as: Diabetes mellitus, renal disease, Liver disease or liver failure, Rheumatoid arthritis, Neoplastic disease or its treatment, chronic corticosteroid therapy, chronic hepatitis B or C , History of hepatitis A, pregnant females.

Design outcomes

Primary

MeasureTime frameDescription
healing of periapical lesioninterappointment at 1 month, 3 months and 6 monthschange in size of bony defect

Countries

Egypt

Contacts

Primary ContactAmira Elkholly, PHD
dr.amiraelkholly@yahoo.com+201001902507
Backup ContactReham Hassan, Ass.prof
reham-hassan@live.com+201001542529

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026