Aging Problems, Wrinkle
Conditions
Keywords
Acupuncture, Thread embedding acupuncture, Aesthetic
Brief summary
This study was aimed to compare the effectiveness of polydioxanone thread embedding acupuncture and manual acupuncture on the reduction of the nasolabial fold. One cycle of therapy in the manual acupuncture group (MA) was carried out with 6 sessions of manual acupuncture therapy while one cycle of therapy in the thread embedding acupuncture group (TEA) received 1 single session of thread embedding acupuncture. The outcome of the study was assessed based on the length of the nasolabial fold as measured by a digital vernier caliper, changes in wrinkle severity rating scale, and patient's subjective opinion of her nasolabial fold using visual analog scale. Outcome measurements were carried out after completing 1 cycle, and follow up at 2 weeks, 1 month, 2 months and 3 months after completing 1 cycle.
Interventions
OTHERManual acupuncture
Manual acupuncture using filiform needle
Thread Embedding acupuncture using Polydioxanone thread
Sponsors
Indonesia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Woman * Age 30-50 years old * WSRS scale 3 to 4 * Willing to follow the research to completion * Subjects who do not have a history of filler injection and/implants, laser therapy, microdermabrasion, peeling, botulinum toxin therapy, manual acupuncture on the face, thread embedding acupuncture on the face and does not either oral or topically use collagen within 6 months * Body mass index of ≥ 18.5 * Signed the informed consent
Exclusion criteria
* Subjects with facial muscle paralysis disorders * Subjects with history of keloids and/or hypertrophic scars, subjects with tumors or infection or inflammation at the treatment area * Subjects with allergies to stainless steel, PDO threads, topical anesthetics lidocaine * Pregnant and lactating subjects * Subjects with cancer * Subjects with history of bleeding disorders or are taking anticoagulant or antiplatelet. * Subjects suffering from fever (≥ 37.5°C), cough, fatigue * Subjects with blood glucose POCT (Point of Care Testing) levels of ≥ 200 mg/dl
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nasolabial fold length | Before intervention (baseline), after completing 1 cycle, at 2 weeks, 1 month, 2 month, and 3 month follow up | Mean difference of nasolabial fold length (measured using digital vernier calipers in millimeters) between two groups |
| Wrinkle severity rating scale (WSRS) | Before intervention (baseline), after completing 1 cycle, at 2 weeks, 1 month, 2 month, and 3 month follow up | Mean difference of WSRS between two groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual analog scale (VAS) | Before intervention (baseline), after completing 1 cycle, at 2 weeks, 1 month, 2 months, and 3 months follow up | Mean difference of VAS (patient's subjective opinion of her nasolabial fold) between two groups |
Countries
Indonesia
Outcome results
None listed